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Table 4 Outcomes for propensity-matched patients

From: Effect of low-dose atrial natriuretic peptide in critically ill patients with acute kidney injury: a retrospective, single-center study with propensity-score matching

Variable

Overall

(n = 628)

Control group

(n = 314)

Treatment group

(n = 314)

p value

Primary outcome

170 (27.1)

79 (25.2)

91 (29.0)

0.281

 In-hospital mortality

129 (20.5)

60 (19.1)

69 (22.0)

0.374

 RRT dependence

22 (3.5)

13 (4.1)

9 (2.9)

0.385

 No AKI recovery

93 (14.8)

42 (13.4)

51 (16.2)

0.312

AKI max-urine output

   

0.123

 No AKI

120 (19.1)

66 (21.0)

54 (17.2)

 

 Stage 1

202 (32.2)

110 (35.0)

92 (29.3)

 

 Stage 2

212 (33.8)

95 (30.3)

117 (37.3)

 

 Stage 3

94 (15.0)

43 (13.7)

51 (16.2)

 

AKI max-creatinine

   

< 0.001

 No AKI

186 (29.6)

135 (43.0)

51 (16.2)

 

 Stage 1

213 (33.9)

92 (29.3)

121 (38.5)

 

 Stage 2

89 (14.2)

31 (9.9)

58 (18.5)

 

 Stage 3

140 (22.3)

56 (17.8)

84 (26.8)

 

AKI max

   

< 0.001

 Stage 1

236 (37.6)

142 (45.2)

94 (29.9)

 

 Stage 2

225 (35.8)

105 (33.4)

120 (38.2)

 

 Stage 3

167 (26.6)

67 (21.3)

100 (31.8)

 

RRT during ICU stay

96 (15.3)

44 (14.0)

52 (16.6)

0.375

ICU LOS (days)

3.8 (2.3–6.9)

2.7 (1.7–4.8)

5.6 (3.7–9.6)

< 0.001

ICU mortality

58 (9.2)

25 (8.0)

33 (10.5)

0.27

Hospital LOS (days)

40 (23–69)

35 (21–62)

44 (26–76)

0.001

Dialysis-free survival

482 (76.8)

243 (77.4)

239 (76.1)

0.706

  1. Data are presented as no. (%) or as median (interquartile range; 25th–75th percentile)
  2. AKI acute kidney injury, AKI max worst stage of AKI, ICU intensive care unit, LOS length of stay, MV mechanical ventilation, No AKI recovery creatinine level ≥ 200% of baseline at hospital discharge, NPPV noninvasive positive-pressure ventilation, RRT renal replacement therapy