Table 1 Demographic characteristics and clinical features in adult-onset minimal change disease on light microscopy
From: IgM mesangial deposition as a risk factor for relapses of adult-onset minimal change disease
Parameters | All | IgM (+) | IgM (−) | p-Value |
|---|---|---|---|---|
Patient number (n) | 37 | 12 | 25 | |
Age (year) | 39.7 ± 16.5 | 38.5 ± 14.9 | 40.3 ± 17.6 | 0.755 |
Male gender (n; %) | 16; 43.2 | 5; 41.7 | 11; 44.0 | 0.893 |
Body weight (kg) | 65.6 ± 13.0 | 64.7 ± 11.5 | 66.0 ± 13.8 | 0.777 |
Blood pressure | ||||
Systolic blood pressure (mmHg) | 129.4 ± 23.6 | 134.9 ± 28.3 | 126.8 ± 21.1 | 0.332 |
Diastolic blood pressure (mmHg) | 82.1 ± 14.9 | 86.8 ± 18.0 | 79.8 ± 12.8 | 0.178 |
Antihypertensive drug use (n; %) | 14; 37.8 | 3; 25.0 | 11; 44.0 | 0.306 |
Lipid profile | ||||
Cholesterol (mg/dL) | 405.0 ± 153.3 | 380.6 ± 116.1 | 415.7 ± 168.2 | 0.535 |
Triglyceride (mg/dL) | 188.3 ± 122.6 | 197.8 ± 83.6 | 183.4 ± 126.6 | 0.726 |
Low density lipoprotein-cholesterol (mg/dL) | 290.6 ± 123.8 | 258.7 ± 104.7 | 304.5 ± 131.9 | 0.427 |
High density lipoprotein-cholesterol (mg/dL) | 82.9 ± 39.6 | 54 ± 25.2 | 92.6 ± 39.8 | 0.152 |
Statin use (n; %) | 22; 59.5 | 7; 58.3 | 15; 60.0 | 1.000 |
Laboratory data at biopsy | ||||
Serum Creatinine (mg/dL) | 1.0 ± 0.6 | 0.8 ± 0.2 | 1.0 ± 0.7 | 0.250 |
eGFR (mL/min/1.73m2) | 97.8 ± 29.9 | 107.1 ± 20.4 | 93.4 ± 33.0 | 0.195 |
Serum Albumin (g/dL) | 2.2 ± 0.9 | 2.4 ± 1.1 | 2.2 ± 0.8 | 0.507 |
UPCR (g/g) | 8.2 ± 4.9 | 7.3 ± 4.3 | 8.6 ± 5.2 | 0.465 |
Urine RBC (/HPF) | 8.4 ± 16.4 | 12.3 ± 27.8 | 6.4 ± 6.2 | 0.482 |
Serum IgM (mg/dL) | 164.8 ± 117.7 | 201.9 ± 171.9 | 147.0 ± 78.8 | 0.188 |
Serum IgM/IgG (%) | 36.6 ± 52.7 | 50.6 ± 88.6 | 29.8 ± 20.7 | 0.267 |