Table 1 Baseline characteristics of 337 IgAN patients at diagnosis

Age (years)

30.0 (24.0, 40.0)

Female (n, %)

192 (57.0)

Weight (kg)

59.5 ± 11.2

Systolic blood pressure (mmHg)

125.8 ± 16.4

Diastolic blood pressure (mmHg)

80.4 ± 12.3

Mean arterial pressure (mmHg)

95.5 ± 12.7

Hypertension (%)

24.6

Anemia (%)

16.0

Hemoglobin (g/L)

130.3 ± 18.4

Serum albumin (g/L)

37.6 (33.3, 41.0)

eGFR (ml/min/1.73m²)

92.4 ± 32.3

Serum creatinine (μmol/L)

78.8 (60.2, 99.5)

Triglyceride (mmol/L)

1.9 ± 2.1

Cholesterol (mmol/L)

5.2 ± 2.2

Serum IgA (g/L)

2.7 ± 1.1

Serum IgG (g/L)

10.3 ± 3.3

Serum IgM (g/L)

1.4 ± 0.7

Serum C3 (g/L)

1.0 ± 0.3

Serum C4 (g/L)

0.3 ± 0.2

Proteinuria (g/24 h)

0.6 (0.3, 1.6)

Immunosuppression (%)

39.0

Corticosteroid (%)

20.3

Renin-angiotensin system blockade (%)

62.6

Tonsillectomy (%)

19.8

IgA Mesangial-only (n)

251

Mesangial +GCLs (n)

86

IgG (−) (n)

258

Mesangial-only (n)

32

Mesangial +GCLs (n)

33

GCLs-only (n)

14

IgM (−) (n)

199

Mesangial-only (n)

102

Mesangial +GCLs (n)

35

GCLs-only (n)

1

C3 (−) (n)

162

Mesangial-only (n)

127

Mesangial +GCLs (n)

46

GCLs-only (n)

2

Fib (−) (n)

299

Mesangial-only (n)

17

Mesangial +GCLs (n)

19

GCLs-only (n)

2

C1q (−) (n)

303

Mesangial-only (n)

19

Mesangial +GCLs (n)

14

GCLs-only (n)

1

M1 (%)

5.6

E1 (%)

7.4

S1 (%)

71.8

T (1 + 2) (%)

73.9

C (1 + 2) (%)

37.7