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Table 1 Baseline characteristics of 337 IgAN patients at diagnosis

From: Immunofluorescence deposits in the mesangial area and glomerular capillary loops did not affect the prognosis of immunoglobulin a nephropathy except C1q:a single-center retrospective study

Parameters N = 337
Age (years) 30.0 (24.0, 40.0)
Female (n, %) 192 (57.0)
Weight (kg) 59.5 ± 11.2
Systolic blood pressure (mmHg) 125.8 ± 16.4
Diastolic blood pressure (mmHg) 80.4 ± 12.3
Mean arterial pressure (mmHg) 95.5 ± 12.7
Hypertension (%) 24.6
Anemia (%) 16.0
Hemoglobin (g/L) 130.3 ± 18.4
Serum albumin (g/L) 37.6 (33.3, 41.0)
eGFR (ml/min/1.73m2) 92.4 ± 32.3
Serum creatinine (μmol/L) 78.8 (60.2, 99.5)
Triglyceride (mmol/L) 1.9 ± 2.1
Cholesterol (mmol/L) 5.2 ± 2.2
Serum IgA (g/L) 2.7 ± 1.1
Serum IgG (g/L) 10.3 ± 3.3
Serum IgM (g/L) 1.4 ± 0.7
Serum C3 (g/L) 1.0 ± 0.3
Serum C4 (g/L) 0.3 ± 0.2
Proteinuria (g/24 h) 0.6 (0.3, 1.6)
Immunosuppression (%) 39.0
Corticosteroid (%) 20.3
Renin-angiotensin system blockade (%) 62.6
Tonsillectomy (%) 19.8
IgA Mesangial-only (n) 251
Mesangial +GCLs (n) 86
IgG (−) (n) 258
Mesangial-only (n) 32
Mesangial +GCLs (n) 33
GCLs-only (n) 14
IgM (−) (n) 199
Mesangial-only (n) 102
Mesangial +GCLs (n) 35
GCLs-only (n) 1
C3 (−) (n) 162
Mesangial-only (n) 127
Mesangial +GCLs (n) 46
GCLs-only (n) 2
Fib (−) (n) 299
Mesangial-only (n) 17
Mesangial +GCLs (n) 19
GCLs-only (n) 2
C1q (−) (n) 303
Mesangial-only (n) 19
Mesangial +GCLs (n) 14
GCLs-only (n) 1
M1 (%) 5.6
E1 (%) 7.4
S1 (%) 71.8
T (1 + 2) (%) 73.9
C (1 + 2) (%) 37.7
  1. Abbreviations: eGFR estimated glomerular filtration rate, C3 complement 3, C4 complement 4, IgG (−) without IgG deposits, IgM (−) without IgM deposits, C3(−) without C3 deposits, Fib (−) without Fib deposits, C1q (−) without C1q deposits, GCLs glomerular capillary loops, Fib Fibrinogen, M mesangial hypercellularity, E endocapillary hypercellularity, S segmental glomerulosclerosis, T tubular atrophy/interstitial fibrosis, C Cellular or fibrocellular crescents