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Table 5 Comparison of light microscopic findings according to the location of immunofluorescence deposits at diagnosis

From: Immunofluorescence deposits in the mesangial area and glomerular capillary loops did not affect the prognosis of immunoglobulin a nephropathy except C1q:a single-center retrospective study

Parameters N Segmental
glomerulosclerosis (%)
Global
glomerulosclerosis (%)
Crescent
(cellular or fibrocellular) (%)
IgA Mesangial-only 251 9.1 (0.0,18.2) 12.5 (3.2,27.3) 0.0 (0.0,6.4)
  Mesangial +GCLs 86 11.9 (4.0,20.3) 13.3 (5.5,30.8) 0.0 (0.0,9.5)
  P   0.094 0.469 0.107
IgG (−) 258 10.0 (0.0,18.8) 14.3 (0.0,30.0) 0.0 (0.0,7.7)
  Mesangial-only 32 7.5 (0.0,14.1) 9.7 (0.0,29.3) 0.0 (0.0,6.1)
  Mesangial +GCLs 33 9.1 (3.9,17.9) 9.5 (4.2,20.9) 0.0 (0.0,9.8)
  P   0.569 0.350 0.665
IgM (−) 199 10.0 (0.0,18.7) 12.5 (4.0,27.6) 0.0 (0.0,8.3)
  Mesangial-only 102 7.7 (0.0,16.2) 12.5 (0.0,27.6) 0.0 (0.0,4.0) a
  Mesangial +GCLs 35 15.4 (6.7,21.4) 18.9 (6.2,29.4) 0.0 (0.0,7.7)
  P   0.113 0.534 0.034
C3 (−) 162 9.3 (0.0,19.6) 12.5 (4.7,27.2) 0.0 (0.0,7.3)
  Mesangial-only 127 8.3 (0.0,15.4) 12.5 (0.0,29.0) 0.0 (0.0,6.7)
  Mesangial +GCLs 46 12.5 (6.0,20.0) 15.6 (6.6,31.4) 0.0 (0.0,9.6)
  P   0.193 0.525 0.685
Fib (−) 299 10.0 (0.0,18.2) 12.5 (4.0,28.6) 0.0 (0.0,7.7)
  Mesangial-only 17 10.0 (5.6,26.7) 15.0 (4.0,27.5) 0.0 (0.0,7.0)
  Mesangial +GCLs 19 9.1 (0.0,17.6) 20.0 (8.0,24.1) 0.0 (0.0,5.3)
  P   0.526 0.833 0.836
C1q (−) 303 9.5 (0.0,18.2) 12.5 (3.7,27.3) 0.0 (0.0,7.7)
  Mesangial-only 19 15.4 (4.8,25.0) 10.0 (6.2,33.3) 0.0 (0.0,4.0)
  Mesangial +GCLs 14 8.2 (0.0,19.5) 17.7 (11.8,50.2) 0.0 (0.0,1.9)
  P   0.226 0.244 0.520
  1. Abbreviations: Fib Fibrinogen, IgG (−) without IgG deposits, IgM (−) without IgM deposits, C3(−) without C3 deposits, Fib (−) without Fib deposits, C1q (−) without C1q deposits, GCLs glomerular capillary loops
  2. * P compare between the IgA groups
  3. a P compare with (−) group
  4. b P compare with the Mesangial-only group
  5. Statistically significant at P < 0.05
  6. The patients with immune deposits in the GCLs group were excluded due to the small sample size