Table 1 Baseline characteristics of 270 PD patients by PTH categories
Characteristic | Total (n = 270) | Baseline PTH levels (pg/mL) | P-value | ||
|---|---|---|---|---|---|
< 150 (n = 78) | 150–300 (n = 69) | > 300 (n = 123) | |||
Age(years) | 39.9 ± 13.3 | 44.0 ± 14.0 | 37.8 ± 11.6 | 38.6 ± 13.2 | 0.005 |
Male (n,%) | 151(55.9%) | 47(60.3%) | 35(50.7%) | 61(50.4%) | 0.307 |
BMI (kg/m2) | 21.6 ± 3.9 | 21.8 ± 3.9 | 21.4 ± 4.0 | 21.6 ± 3.8 | 0.814 |
Primary cause of ESRD | |||||
Glomerulonephritis | 193(71.5%) | 48(61.5%) | 53 (76.8%) | 92(74.8%) | 0.067 |
Diabetic kidney disease | 24(8.9%) | 12(15.4%) | 7(10.1%) | 5(4.1%) | 0.022 |
Hypertensive kidney disease | 30(11.1%) | 8(10.3%) | 6(8.7%) | 16(13.0%) | 0.633 |
Vasculitis kidney disease | 8(3.0%) | 5(6.4%) | 1(1.4%) | 2 (1.6%) | 0.151 |
Others | 21(7.8%) | 6(7.7%) | 5(7.2%) | 10(8.1%) | 0.976 |
SBP (mmHg) | 141.4 ± 19.7 | 137.5 ± 18.6 | 143.3 ± 20.8 | 142.7 ± 19.5 | 0.187 |
DBP (mmHg) | 91.6 ± 15.7 | 88.8 ± 14.2 | 94.3 ± 17.0 | 91.8 ± 15.5 | 0.158 |
White blood cell (× 109/L) | 6.6 ± 2.1 | 6.9 ± 2.2 | 6.5 ± 2.2 | 6.5 ± 1.9 | 0.220 |
Neutrophil (× 109/L) | 4.5 ± 1.7 | 4.8 ± 1.8 | 4.6 ± 2.0 | 4.4 ± 1.5 | 0.321 |
Lymphocyte (×109/L) | 1.5 ± 0.5 | 1.6 ± 0.6 | 1.4 ± 0.4 | 1.4 ± 0.5 | 0.103 |
Hemoglobin (g/L) | 100.8 ± 22.0 | 107.3 ± 21.7 | 98.3 ± 21.7 | 98.1 ± 21.6 | 0.008 |
Platelet (×109/L) | 195.7 ± 74.9 | 202.1 ± 73.0 | 205.3 ± 83.9 | 186.3 ± 70.1 | 0.160 |
Urea nitrogen (mmol/L) | 14.9 ± 7.6 | 13.7 ± 7.3 | 15.4 ± 8.1 | 15.4 ± 7.4 | 0.272 |
Creatinine (umol/L) | 764.1(590.4–1017.4) | 701.9(539.3–909.7) | 786.8(628.3–1094.6) | 791.7(613.2–1084.6) | 0.023 |
eGFR (/kg/m2) | 8.1 (6.0–10.3) | 9.2(6.7–11.3) | 7.7(6.3–9.4) | 7.8(5.7–9.9) | 0.069 |
Uric acid (umol/L) | 421.1 ± 108.8 | 420.3 ± 95.9 | 423.3 ± 116.1 | 420.3 ± 112.9 | 0.981 |
Calcium (mmol/L) | 2.2 ± 0.2 | 2.3 ± 0.2 | 2.2 ± 0.2 | 2.1 ± 0.2 | 0.000 |
Phosphate (mmol/L) | 1.4 ± 0.5 | 1.3 ± 0.5 | 1.5 ± 0.4 | 1.5 ± 0.5 | 0.001 |
PTH (pg/mL) | 260.05 (121.7–447.0) | 74.5(28.3–109.9) | 226.7(185.8–258.9) | 475.3(364.0–694.7) | 0.000 |
Alkaline phosphatase (U/L) | 74.0(60.0–98.5) | 64.0(56.0–83.3) | 70.0(61.5–89.5) | 82.5 (68.0–122.5) | 0.000 |
Cholesterol (mmol/L) | 4.7 ± 1.1 | 4.8 ± 1.2 | 4.8 ± 1.2 | 4.7 ± 1.0 | 0.788 |
Triglyceride (mmol/L) | 1.7 ± 0.9 | 1.9 ± 1.1 | 1.6 ± 0.8 | 1.6 ± 0.8 | 0.063 |
Total protein(g/L) | 64.1 ± 8.5 | 64.4 ± 9.5 | 63.8 ± 6.9 | 64.1 ± 8.7 | 0.925 |
Albumin(g/L) | 35.3 ± 6.0 | 35.9 ± 6.7 | 35.4 ± 5.2 | 34.9 ± 6.0 | 0.519 |
C-reactive protein(mmol/L) | 1.17(0.61,4.91) | 2.02(0.61,11.2) | 1.1(0.5,6.2) | 1.1(0.7,4.9) | 0.768 |
Active vitamin D use (n, %) | 161(59.6%) | 25(32.1%) | 34(49.3%) | 102(82.9%) | 0.000 |