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Table 3 Three-way ANOVA-generated marginal means of CLTM by CRRT mode, filter type, and flow rate

From: Pharmacokinetics and dialytic clearance of apixaban during in vitro continuous renal replacement therapy

CLTM by SC or SA

CRRT mode

Filter type

Flow rate (L/h)

CLTM (L/h)

95% CI

SE

CVVH

HF1400

2

1.438

1.105–1.772

0.157

4

2.490

1.913–3.067

0.272

M150

2

1.507

1.173–1.840

0.157

4

2.160

1.583–2.737

0.272

CVVHD

HF1400

2

1.245

0.668–1.822

1.245

4

2.405

1.828–2.982

2.405

M150

2

1.240

0.663–1.817

0.272

4

2.225

1.648–2.802

0.272

CLTM by AUC

CVVH

HF1400

2

1.803

1.596–2.011

0.980

4

3.300

2.941–3.659

0.170

M150

2

1.118

0.911–1.326

0.098

4

2.070

1.711–2.429

0.170

CVVHD

HF1400

2

1.665

1.306–2.024

0.170

4

2.165

1.806–2.524

0.170

M150

2

0.905

0.546–1.264

0.170

4

1.630

1.271–1.989

0.170

  1. SE standard error