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Table 4 Multiple linear regression between tested covariates and CLTM by AUC

From: Pharmacokinetics and dialytic clearance of apixaban during in vitro continuous renal replacement therapy

Variable

Unstandardized β

95% CI

P value

Constant

1.469

0.800–2.137

< 0.001

Filter typea

−0.821

−1.133 - -0.509

< 0.001

Flow rate (L/h)

0.612

0.864–1.585

< 0.001

  1. aHF1400 = 1, M150 = 2
  2. Variables entered: CRRT mode, filter type, flow rate, and point of dilution
  3. Adjusted R2 = 0.849
  4. Regression equation: CLTM = 1.469 L/h + (− 0.821 * filter type) + (0.612 * flow rate (L/h))