Table 1 Baseline patient characteristics
All Median [Quartile 1 - Quartile 3] or n (%) N = 466 | Renal improver (RI) Median [Quartile 1 - Quartile 3] or n (%) N = 255 | Non-Improver (non-RI) Median [Quartile 1 - Quartile 3] or n (%) N = 211 | P-value (RI vs. non-RI) | |
|---|---|---|---|---|
Age (years) | 81 [77–86] | 82 [78–87] | 81 [77–85] | 0.006 |
Males | 200 (42.9) | 97 (38.0) | 103 (48.8) | 0.019 |
Body-Mass-Index (kg/m2) | 26.30 [23.44–29.63] | 26.01 [23.03–29.14] | 26.77 [23.83–30.25] | 0.049 |
LVEF < 35% | 49 (10.5) | 27 (10.6) | 22 (10.4) | 0.582 |
NYHA class III or IV | 328 (70.4) | 190 (74.5) | 138 (65.4) | 0.070 |
Comorbidities | ||||
Coronary artery disease | 327 (70.2) | 182 (71.4) | 145 (68.7) | 0.533 |
Atrial fibrillation | 204 (43.8) | 117 (45.9) | 87 (41.2) | 0.314 |
Hypertension | 422 (90.6) | 230 (90.2) | 192 (91.0) | 0.769 |
Dyslipidemia | 228 (48.9) | 119 (46.7) | 109 (51.7) | 0.283 |
Cerebrovascular disease | 84 (18.0) | 45 (17.6) | 39 (18.5) | 0.81 |
Diabetes mellitus | 141 (30.3) | 77 (30.2) | 64 (30.3) | 0.975 |
Peripheral artery disease | 63 (13.5) | 31 (12.2) | 32 (15.2) | 0.344 |
COPD | 60 (12.9) | 33 (12.9) | 27 (12.8) | 0.963 |
Dialysis | 5 (1.1) | 3 (1.2) | 2 (0.9) | 0.812 |
Logistic EuroSCORE | 16.05 [9.69–24.34] | 16.35 [10.36–24.40] | 15.70 [9.00–24.23] | 0.284 |
EuroSCORE II | 4.32 [2.73–7.36] | 4.66 [3.04–7.69] | 3.92 [2.43–6.77] | 0.011 |
STS score (%) | 4.38 [2.86–6.50] | 4.43 [3.10–6.52] | 4.30 [2.56–6.48] | 0.167 |
NT-proBNP (ng/l) | 1816 [714–3928] | 2183 [706–4348] | 1489 [715–3276] | 0.054 |
hsTNT (pg/ml) | 25.40 [15.70–45.55] | 25.40 [16.80–50.10] | 25.40 [15.00–42.20] | 0.298 |
eGFR (ml/min/1.73m2) | 54 [37–76] | 49 [34–72] | 56 [43–78] | 0.001 |
Creatinine (μmol/l) | 99.12 [78.41–124.20] | 103.55 [79.0–137.0] | 96.55 [77.88–118.00] | 0.021 |
Urea (mmol/l) | 7.30 [5.55–10.55] | 7.70 [5.70–11.49] | 6.83 [5.49–9.70] | 0.010 |
CRP (mg/l) | 3.7 [1.4–11.1] | 4.0 [1.6–11.7] | 3.3 [1.4–9.5] | 0.431 |