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Table 1 Description of the recipients’ characteristics according to obesity status

From: Renal transplantation outcomes in obese patients: a French cohort-based study

 

Whole sample

(n = 4691)

Non-obese

(n = 3944)

Obese

(n = 747)

p-value

NA

n

%

NA

n

%

NA

n

%

 

Male

0

2977

63.5

0

2563

65.0

0

414

55.4

< 0.0001

Recurrent causal nephropathy (*)

1

1114

23.8

1

983

24.9

0

131

17.5

< 0.0001

Causal nephropathy

1

  

1

  

0

  

< 0.0001

Diabetes

 

569

12.1

 

392

9.9

 

177

23.6

 

Glomerulopathy

 

935

19.8

 

823

20.8

 

112

15.0

 

Other

 

2252

47.8

 

1963

49.5

 

289

38.6

 

Tubulointerstitial nephritis

 

414

8.8

 

352

8.9

 

62

8.3

 

Vascular disease

 

540

11.5

 

431

10.9

 

109

14.6

 

Preemptive transplantation

8

450

9.6

8

395

10.0

0

55

7.4

0.0231

Peritoneal dialysis

8

454

9.7

8

398

10.1

0

55

7.4

0.0240

History of diabetes

0

923

19.7

0

637

16.2

0

286

38.3

< 0.0001

History of hypertension

0

3949

84.2

0

3301

83.7

0

648

86.7

0.0362

History of vascular disease

0

837

17.8

0

696

17.6

0

141

18.9

0.4214

History of cardiac disease

0

1355

28.9

0

1095

27.8

0

260

34.8

0.0001

History of cardiovascular disease

0

1806

38.5

0

1475

37.4

0

331

44.3

0.0004

History of malignancy

0

476

10.1

0

406

10.3

0

70

9.4

0.4435

History of dyslipidemia

0

1934

41.2

0

1516

38.4

0

418

56.0

< 0.0001

History of B or C hepatitis

0

250

5.3

0

224

5.7

0

26

3.5

0.0142

Positive CMV serology

47

3028

65.2

40

2515

64.4

7

513

69.3

0.0102

Positive EBV serology

62

4488

97.0

53

3765

96.8

9

723

98.0

0.0806

Positive class I anti-HLA antibodies

378

1369

31.7

318

1145

31.6

60

224

32.6

0.5956

Positive class II anti-HLA antibodies

432

1223

28.7

360

1033

28.8

72

190

28.1

0.7224

Blood group

3

  

1

  

2

  

0.4660

A

 

2018

43.0

 

1695

43.0

 

323

43.4

 

AB

 

221

4.7

 

178

4.5

 

43

5.8

 

B

 

533

11.4

 

448

11.4

 

85

11.4

 

O

 

1916

40.9

 

1622

41.1

 

294

39.5

 

HLA A-B-DR incompatibilities ≥ 4

43

720

15.5

34

610

15.6

9

110

14.9

0.6318

ABO incompatible transplants

0

1

0.1

0

6

0.2

0

1

0.1

1.0000

Depleting induction

0

2505

53.4

0

2060

52.2

0

445

59.6

0.0002

Maintenance therapy

Calcineurin inhibitors

0

4611

97.9

0

3873

97.8

0

738

98.5

0.2240

Corticosteroids

0

4832

93.0

0

3683

93.0

0

699

93.3

0.7775

Age ≥ 55 years

0

2435

51.9

0

1984

50.3

0

451

60.4

< 0.0001

 

NA

mean

sd

NA

mean

sd

NA

mean

sd

p-value

Waiting list (months)

108

25.9

22.7

91

25.9

22.8

17

25.6

21.7

0.6865

Age (years)

0

53.5

13.2

0

52.9

13.5

0

56.2

11.2

< 0.0001

Cold ischemia time (hours)

18

18.1

7.4

13

18.1

7.5

5

18.3

7.1

0.4490

  1. Abbreviations: HLA Human Leucocyte Antigen, CMV Cytomegalovirus, EBV Epstein-Barr Virus