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Table 1 Baseline characteristics of included studies

From: Morbidity after elective surgery in patients on chronic dialysis: a systematic review and meta-analysis

Author

Country

Type of Surgery

Dialysis type

Total number of patients in study (n)

Mean age years (SD) or Median age [IQR]

Ischemic heart disease (%)

Diabetes (%)

Outcomes reported

Normal kidney function

Dialysis patients

Normal kidney function

Dialysis patients

Normal kidney function

Dialysis patients

Normal kidney function

Dialysis patients

 

Cardiac Surgery

 Al Sarraf, 2011

Ireland

Coronary artery bypass graft & Valve

Unspecified

3,276

45

63.2 (10.2)

62 (12.3)

2,763 (84.3)

36 (80)

560 (17.1)

10 (22.2)

Stroke, Sepsis, Pneumonia, Return to Operating theatre, Blood transfusion

 Charytan, 2007

USA

Coronary artery bypass graft & Valve

Both

77,323

635

66.1a

62.9a

14,619 (18.9)

253 (39.8)

23,208 (30.0)

367 (57.8)

Stroke, Sepsis, Pneumonia,

 Chikwe,2010

USA

Coronary artery bypass graft

Unspecified

2,803

96

65.6 (0.7)

63.3 (10.7)

1,398 (49.9)

52 (54.2)

1,092 (38.9)

69 (71.9)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre

 Cooper, 2006

USA

Coronary artery bypass graft & Valve

Unspecified

104,880

7,152

58.9a

63a

9,439 (8.9)

1,595 (22.3)

31,464 (30)

4,363 (61.0)

Stroke, Sepsis, Surgical site infection, Return to Operating theatre

 Fukushima, 2005

Japan

Coronary artery bypass graft

HD

451

20

67.2 (8)

63.9 (8)

451 (100)

20 (100)

243 (53.9)

13 (65)

Stroke, Pneumonia

 Griffin, 2019

USA

Coronary artery bypass and valve

HD

1,416

35

62.6 (14.3)

58.8 (13.0)

1,416 (100)

35 (100)

434 (30.7)

22 (62.9)

Surgical site infection, Sepsis, Pneumonia, Stroke,

 Kan, 2004

Taiwan

Coronary artery bypass graft

Both

69

23

63.8 (11.2)

63.8 (9.9)

23 (33.3)

23 (100)

34 (49.3)

15 (65.2)

Sepsis, Surgical site infection, Return to Operating theatre

 Murai, 2007

Japan

Coronary artery bypass graft

HD

60

39

67.2 (7.9)

63.2 (10.2)

60 (100)

39 (100)

NR

NR

Blood transfusion

 Rahmanian, 2008

USA

Coronary artery bypass graft

Unspecified

6,449

245

63.9 (13.8)

61.3 (13.2)

1,548 (30.1)

81 (33.1)

1,548 (24.0)

104 (42.4)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Return to Operating theatre, Blood transfusion

 Raza, 2017

USA

Valve surgery

HD

199

144

58a

55a

NR

NR

NR

NR

Myocardial infarction, Stroke, Sepsis, Return to Operating theatre

 Yamauchi, 2012

Japan

Coronary artery bypass graft

HD

18,387

1300

68.7 (9.4)

65.4 (9.2)

NR

NR

8,826 (48.0)

854 (65.7)

Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre, DVT/PE, Blood transfusion

 Wong, 2003

Canada

Coronary artery bypass graft

Unspecified

70

35

64 (11)

64 (11)

32 (45.7)

14 (40)

31 (44.3)

8 (22.9)

Myocardial infarction, Stroke, Surgical site infection, Return to Operating theatre, Blood transfusion

 Vasileva, 2014

USA

Cardiac Valve surgery

Unspecified

85,083

1,480

63 [52–72]

55 [45–65]

NR

NR

10,295 (12.1)

463 (31.3)

Stroke, Surgical site infection, Pneumonia, Return to Operating theatre, Blood transfusion

 Thourani, 2012

USA

Coronary artery bypass graft and Valve

Haemodialysis

5,084

224

61 (14.8)

54 (14.0)

798 (15.7)

46 (20.5)

933 (18.4)

87 (38.8)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre

General Surgery

 Andalib, 2016

USA

Bariatric procedures

Both

113,677

234

44.7 (11.6)

47.3 (10.4)

154 (0.1)

1 (0.4)

30,602 (26.9)

112 (47.9)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre, DVT/PE, Blood transfusion

 Barbas, 2014

USA

Hepatobiliary

Both

27,275

101

62 [53–71]

60 [53–68]

2,204 (8.1)

17 (16.8)

5,431 (19.9)

48 (47.5)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre, DVT/PE

 Cherng, 2013

Taiwan

General

Both

8,937

8,937

65a

65.5a

3,965 (44.4)

3,930 (43.9)

4,628 (51.8)

4,589 (51.3)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia

 Cloyd, 2014

USA

General

HD

24,110

149

61.3 (15.5)

62.3 (13.4)

NR

NR

NR

NR

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, DVT/PE

 Ekici, 2009

Turkey

Laparoscopic Cholecystectomy

PD

33

11

45.6 (11)

44.2 (9.1)

NR

NR

NR

NR

Sepsis, Surgical site infection, Blood transfusion

 Gajdos, 2013

USA

General surgery

Both

164,094

1,506

55.4 (16.8)

59.6 (15.1)

1,590 (1.0)

100 (6.6)

26,764 (16.3)

583 (38.7)

Myocardial infarction, Stroke, Surgical site infection, Pneumonia, Return to Operating theatre, DVT/PE

 Hu, 2015

USA

Colorectal Surgery (General)

Unspecified

42,138

265

70 [31–90]

67 [19–90]

NR

NR

131 (49.4)

7760 (18.4)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre, DVT/PE, Blood transfusion

 Manrique, 2017

Taiwan

Skin grafting for head and neck reconstruction

Unspecified

841

85

55.9 (10.0)

56.3 (10.5)

NR

NR

139 (16.5)

52 (61.2)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, DVT/PE

 Montgomery, 2019

USA

Bariatric surgery

Unspecified

417,403

1,244

44.2 [35.7–53.3]

49.0 [41.6–55.8]

12,497 (3.0)

199 (16.0)

109,509 (26.2)

690 (55.5)

Myocardial infarction, stroke, pneumonia, DVT/PE, Surgical site infection, Sepsis, Blood transfusion, Return to Operating theatre

 Rao, 2014

USA

Cholecystectomy

Unspecified

80,483

512

48.9 (17.4)

59.8 (14.9)

563 (0.7)

26 (0.1)

8,853 (11.0)

235 (45.9)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre, DVT/PE, Blood transfusion

 Schneider, 2009

USA

General

Unspecified

108

54

59.8a

59.3a

NR

NR

NR

NR

Stroke, Sepsis, Surgical site infection

 Tam, 2015

USA

Ventral hernia

(General)

Unspecified

90,993

700

53.5 (14.5)

56.7 (13.5)

7,097 (7.8)

160 (22.9)

12,189 (13.4)

214 (30.6)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre, DVT/PE, Blood transfusion

Orthopaedic Surgery

 Cancienne, 2019

USA

Shoulder arthroplasty

Both

3,675

1,225

67.5a

67.5a

2,570 (69.9)

881 (71.9)

2,766 (75.3)

922 (75.3)

Sepsis, Return to Operating theatre

 Chikuda, 2012

Japan

Spinal surgery

HD

50,779

869

62.3 (15.6)

64.3 (8.2)

2,597 (5.1)

126 (14.5)

6252 (12.3)

166 (19.1)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, DVT/PE

 Chung, 2017

USA

Spinal surgery

Unspecified

2,522,594

1,834

59.9 (14.7)

64.2 (11.6)

48,814 (1.9)

273 (14.9)

421,178 (16.7)

907 (49.5)

Myocardial infarction, Stroke, Sepsis, Pneumonia, DVT/PE, Blood transfusion

 Hickson, 2018

USA

Hip arthroplasty

Both

1,508

377

78 [68–85]

77 [67–84]

NR

NR

648 (43.0)

162 (43.0)

Surgical site infection, Pneumonia, DVT/PE, Myocardial infarction, Sepsis

 Inoue, 2018

Japan

Spinal Surgery

Unspecified

863

90

72.3 [30–92]

69.9 [48–68]

109 (12.6)

16 (17.8)

201 (23.3)

27 (30)

Surgical site infection, Myocardial infarction, Stroke, Blood transfusion

 Lin, 2019

Taiwan

Hip Hemiarthroplasty

Unspecified

19,954

1,311

73.5 ± 11.2

70.7 ± 8.8

3,913 (19.6)

466 (35.5)

NR

NR

Surgical site infection, Pneumonia, Blood transfusion, Return to Operating theatre

 Lizaur-Utrilla, 2016

Spain

Arthroplasty

HD

30

15

70.1 [58–72]

69.3 [56–72]

8 (26.7)

4 (26.7)

7 (23.3)

6 (40)

Myocardial infarction, Sepsis, Surgical site infection, Pneumonia, DVT/PE, Blood transfusion

 Ottesen, 2018

USA

Spinal surgery

Unspecified

173,311

467

57.0 (5.5)

63 (7.0)

NR

NR

NR

NR

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre, DVT/PE

 Ottesen, 2018

USA

Total knee arthroplasty

Unspecified

163,560

250

67.0 (7.0)

68.0 (7.0)

NR

NR

NR

NR

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre, DVT/PE

 Ponumsamy, 2015

USA

Arthroplasty

Unspecified

6,186,475

2,934

66.8 (0.1)

66.7 (0.6)

NR

NR

NR

NR

Surgical site infection, Blood transfusion

 Yu, 2011

Taiwan

Spinal surgery (Orthopaedic)

HD

34

43

61.5 (8.1)

62.5 (8.1)

NR

NR

3 (8.8)

7 (16.3)

Sepsis, Return to Operating theatre, Blood transfusion

Vascular surgery

 Ambur, 2019

USA

Lower extremity bypass

Both

6,101

550

68.2 (11.7)

66.4 (10.7)

188 (3.0)

42 (7.6)

2,924 (47.9)

349 (63.5)

Myocardial infarction, Return to Operating theatre

 Balceniuk, 2019

USA

Distal lower extremity bypass

Both

12,006

1,014

68.4a

67.3a

209 (2.0)

29 (3.0)

5501 (57.0)

784 (81.0)

Myocardial infarction, Stroke

 Gajdos, 2013

USA

Vascular procedures involving both peripheral arteries, carotid and aorta.

Both

34,813

1,409

70.3 (10.8)

64.3 (13.8)

7,129 (20.5)

335 (23.8)

9,029 (25.9)

726 (51.5)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Return to Operating theatre, DVT/PE

 Hibino, 2016

Japan

Abdominal aortic aneurysm repair (Vascular)

HD

679

21

65.7 (13)

63.5 (15.5)

NR

NR

79 (11.6)

9 (42.9)

Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre, Blood transfusion

 Hickson, 2018

USA

Lower extremity amputation

Unspecified

5,302

1,166

68.0 (11.0)

65.0 (7.5)

NR

NR

3,085 (58.2)

882 (75.6)

Myocardial infarction, Sepsis, Surgical site infection, Pneumonia

 Lantis, 2001

USA

Infrainguinal bypass

Unspecified

481

60

69a

63.0a

241 (50.1)

38 (63.3)

212 (44.1)

50 (83.3)

Myocardial infarction,

 O Hare 2003

USA

Non-traumatic lower limb amputation

Unspecified

11,051

1,110

68a

68a

884 (8.0)

189 (17.0)

5,747 (52.0)

799 (72.0)

Myocardial infarction, Stroke, Sepsis, Pneumonia, DVT/PE, Blood transfusion

 Rao, 2017

USA

Infrainguinal bypass (Vascular)

Both

33,318

1,623

66.7 (11.0)

66.0 (10.7)

433 (1.3)

73 (4.5)

12,228 (36.7)

1,034 (63.7)

Myocardial infarction, Stroke, Sepsis, Surgical site infection, Pneumonia, Return to Operating theatre, DVT/PE

Urology/gynaecology surgery

 

 Fornara, 1998

Germany

Laparoscopic Nephrectomy

HD

20

19

38 [24–70]

45 [20–73]

NR

NR

NR

NR

Myocardial infarction, Sepsis, Pneumonia, Blood transfusion

 May, 2018

USA

Laprascopic nephrectomy

Both

7,870

445

55

55

56 (0.7)

14 (3.1)

1,637 (20.8)

141 (31.7)

Surgical site infections, Sepsis, Pneumonia, DVT/PE, Blood transfusion

 Schmitges, 2012

USA

Nephrectomy (Urologic/Gynaecologic)

Unspecified

3,764

941

59 (12.8)

59.1 (12.7)

NR

NR

NR

NR

Surgical site infection, Blood transfusion

 Yamashita, 2012

Japan

Nephrectomy

(Urologic/Gynaecologic)

Both

104

38

61.9 (14.1)

58.3 (11.4)

NR

NR

NR

NR

Sepsis, Surgical site infection, Pneumonia

  1. aStandard deviation or interquartile range not provided