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Table 3 Stratified analysis of ESRD incidence according to baseline eGFR and TUG categories

From: Association between physical performance and incidence of end-stage renal disease in older adults: a national wide cohort study

eGFR (MDRD)

TUG

Subjects

ESRD incidence

Incidence ratioa

Model 1

Model 2

Model 3

Model 4

Competing risk model

15–29

−10

1713

659

104.26

1 (ref.)

1 (ref.)

1 (ref.)

1 (ref.)

1 (ref.)

10–14.9

627

223

97.53

0.94 (0.81–1.09)

0.98 (0.84–1.14)

0.96 (0.82–1.11)

0.99 (0.85–1.15)

0.96 (0.82–1.12)

151–9.9

112

52

124.65

1.20 (0.90–1.59)

1.32 (0.99–1.75)

1.26 (0.95–1.68)

1.19 (0.89–1.58)

1.12 (0.86–1.47)

20–

33

11

105.54

1.02 (0.56–1.86)

1.32 (0.73–2.40)

1.12 (0.62–2.05)

1.41 (0.78–2.58)

0.76 (0.37–1.58)

30–59

−10

114,180

1120

1.89

1 (ref.)

1 (ref.)

1 (ref.)

1 (ref.)

1 (ref.)

10–14.9

37,043

413

2.04

1.05 (0.93–1.17)

1.12 (1.00–1.25)

1.02 (0.91–1.14)

1.04 (0.93–1.16)

1.03 (0.92–1.16)

15–19.9

5510

71

2.25

1.13 (0.89–1.44)

1.22 (0.96–1.56)

1.03 (0.81–1.32)

0.97 (0.76–1.23)

0.93 (0.72–1.21)

20–

1053

16

2.72

1.37 (0.84–2.25)

1.55 (0.95–2.55)

1.08 (0.66–1.77)

1.00 (0.61–1.64)

0.94 (0.56–1.58)

60–89

−10

798,406

802

0.20

1 (ref.)

1 (ref.)

1 (ref.)

1 (ref.)

1 (ref.)

10–14.9

219,894

284

0.25

1.19 (1.04–1.36)

1.21 (1.05–1.38)

1.16 (1.01–1.33)

1.13 (0.99–1.30)

1.11 (0.97–1.28)

15–9.9

29,361

48

0.30

1.38 (1.03–1.85)

1.40 (1.04–1.87)

1.31 (0.97–1.75)

1.24 (0.93–1.66)

1.22 (0.90–1.64)

20–

4851

15

0.57

2.67 (1.60–4.46)

2.71 (1.63–4.53)

2.41 (1.44–4.01)

2.15 (1.29–3.59)

2.09 (1.25–3.50)

≥90

−10

244,827

151

0.13

1 (ref.)

1 (ref.)

1 (ref.)

1 (ref.)

1 (ref.)

10–14.9

82,712

64

0.15

1.18 (0.88–1.57)

1.20 (0.89–1.60)

1.17 (0.87–1.57)

1.16 (0.87–1.55)

1.15 (0.86–1.56)

15–19.9

10,701

6

0.11

0.83 (0.37–1.88)

0.86 (0.38–1.94)

0.81 (0.36–1.82)

0.81 (0.36–1.83)

0.83 (0.37–1.87)

20–

1758

3

0.34

2.59 (0.82–8.11)

2.66 (0.85–8.36)

2.53 (0.81–7.93)

2.52 (0.80–7.90)

2.48 (0.79–7.79)

  1. Model 1: crude model; Model 2: Adjusting for sex, smoking status, alcohol history, exercise level, and income; Model 3: adjusting for variables of Model 2 with BMI, DM, HT, dyslipidemia, and eGFR; Model 4: adjusting for variables of Model 3 and state of dipstick proteinuria (4 categories); Competing risk model: adjusting for variables in Model 4 and considering competing risk
  2. BMI body mass index, DM diabetes mellitus, eGFR estimated glomerular filtration rate using the abbreviated Modification of Diet in Renal Disease formula, ESRD end-stage renal disease, HT hypertension, TUG timed up-and-go test
  3. aPer 1000 person-years