|
eGFR (CKD-EPI)
|
TUG
|
Subjects
|
ESRD incidence
|
Incidence ratioa
|
Model 1
|
Model 2
|
Model 3
|
Model 4
|
|---|
|
15–29
|
−10
|
1868
|
699
|
101.09
|
1 (ref.)
|
1 (ref.)
|
1 (ref.)
|
1 (ref.)
|
|
10–14.9
|
671
|
239
|
97.19
|
0.96 (0.82–1.12)
|
1.00 (0.87–1.16)
|
0.98 (0.84–1.13)
|
1.2 (0.88–1.18)
|
|
15–19.9
|
125
|
55
|
115.72
|
1.14 (0.87–1.50)
|
1.20 (0.91–1.58)
|
1.21 (0.92–1.60)
|
1.17 (0.88–1.54)
|
|
20-
|
34
|
11
|
102.72
|
1.03 (0.57–1.87)
|
1.28 (0.70–2.33)
|
1.11 (0.61–2.02)
|
1.43 (0.78–2.60)
|
|
30–59
|
−10
|
114,006
|
1078
|
1.82
|
1 (ref.)
|
1 (ref.)
|
1 (ref.)
|
1 (ref.)
|
|
10–14.9
|
36,997
|
397
|
1.96
|
1.04 (0.93–1.17)
|
1.11 (0.99–1.25)
|
1.02 (0.91–1.14)
|
1.02 (0.91–1.15)
|
|
15–19.9
|
5496
|
68
|
2.16
|
1.12 (0.88–1.43)
|
1.21 (0.95–1.55)
|
1.07 (0.84–1.37)
|
0.97 (0.76–1.24)
|
|
20-
|
1052
|
16
|
2.72
|
1.42 (0.87–2.33)
|
1.60 (0.97–2.61)
|
1.10 (0.67–1.80)
|
1.00 (0.61–1.64)
|
|
60–89
|
−10
|
643,658
|
710
|
0.22
|
1 (ref.)
|
1 (ref.)
|
1 (ref.)
|
1 (ref.)
|
|
10–14.9
|
171,381
|
246
|
0.27
|
1.20 (1.04–1.39)
|
1.21 (1.04–1.40)
|
1.16 (1.00–1.34)
|
1.13 (0.98–1.31)
|
|
15–19.9
|
22,505
|
43
|
0.34
|
1.45 (1.07–1.98)
|
1.46 (1.07–1.98)
|
1.36 (1.00–1.85)
|
1.29 (0.95–1.75)
|
|
20-
|
3684
|
13
|
0.64
|
2.72 (1.57–4.71)
|
2.74 (1.58–4.74)
|
2.43 (1.41–4.22)
|
2.13 (1.23–3.70)
|
|
≥90
|
−10
|
399,594
|
245
|
0.13
|
1 (ref.)
|
1 (ref.)
|
1 (ref.)
|
1 (ref.)
|
|
10–14.9
|
131,227
|
102
|
0.15
|
1.18 (0.94–1.49)
|
1.18 (0.94–1.49)
|
1.15 (0.91–1.44)
|
1.13 (0.90–1.43)
|
|
15–19.9
|
17,558
|
11
|
0.12
|
0.92 (0.50–1.68)
|
0.92 (0.50–1.68)
|
0.87 (0.47–1.58)
|
0.86 (0.47–1.57)
|
|
20-
|
2925
|
5
|
0.34
|
2.60 (1.07–6.30)
|
2.56 (1.06–6.21)
|
2.37 (0.98–5.74)
|
2.39 (0.99–5.80)
|
- Model 1: crude model; Model 2: adjusting for sex, smoking status, alcohol history, exercise level, and income; Model 3: adjusting for variables of Model 2 with BMI, DM, HT, dyslipidemia, and eGFR; Model 4: adjusting for variables of Model 3 and state of dipstick proteinuria (4 categories)
- BMI body mass index, CKD-EPI Chronic Kidney Disease Epidemiology Collaboration equation based on serum creatinine, DM diabetes mellitus, eGFR estimated glomerular filtration rate, ESRD end-stage renal disease, HT hypertension, TUG timed up-and-go test
- aPer 1000 person-years
