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Table 4 ESRD incidence according to baseline eGFR and TUG categories, using the CKD-EPI eGFR formula

From: Association between physical performance and incidence of end-stage renal disease in older adults: a national wide cohort study

eGFR (CKD-EPI) TUG Subjects ESRD incidence Incidence ratioa Model 1 Model 2 Model 3 Model 4
15–29 −10 1868 699 101.09 1 (ref.) 1 (ref.) 1 (ref.) 1 (ref.)
10–14.9 671 239 97.19 0.96 (0.82–1.12) 1.00 (0.87–1.16) 0.98 (0.84–1.13) 1.2 (0.88–1.18)
15–19.9 125 55 115.72 1.14 (0.87–1.50) 1.20 (0.91–1.58) 1.21 (0.92–1.60) 1.17 (0.88–1.54)
20- 34 11 102.72 1.03 (0.57–1.87) 1.28 (0.70–2.33) 1.11 (0.61–2.02) 1.43 (0.78–2.60)
30–59 −10 114,006 1078 1.82 1 (ref.) 1 (ref.) 1 (ref.) 1 (ref.)
10–14.9 36,997 397 1.96 1.04 (0.93–1.17) 1.11 (0.99–1.25) 1.02 (0.91–1.14) 1.02 (0.91–1.15)
15–19.9 5496 68 2.16 1.12 (0.88–1.43) 1.21 (0.95–1.55) 1.07 (0.84–1.37) 0.97 (0.76–1.24)
20- 1052 16 2.72 1.42 (0.87–2.33) 1.60 (0.97–2.61) 1.10 (0.67–1.80) 1.00 (0.61–1.64)
60–89 −10 643,658 710 0.22 1 (ref.) 1 (ref.) 1 (ref.) 1 (ref.)
10–14.9 171,381 246 0.27 1.20 (1.04–1.39) 1.21 (1.04–1.40) 1.16 (1.00–1.34) 1.13 (0.98–1.31)
15–19.9 22,505 43 0.34 1.45 (1.07–1.98) 1.46 (1.07–1.98) 1.36 (1.00–1.85) 1.29 (0.95–1.75)
20- 3684 13 0.64 2.72 (1.57–4.71) 2.74 (1.58–4.74) 2.43 (1.41–4.22) 2.13 (1.23–3.70)
≥90 −10 399,594 245 0.13 1 (ref.) 1 (ref.) 1 (ref.) 1 (ref.)
10–14.9 131,227 102 0.15 1.18 (0.94–1.49) 1.18 (0.94–1.49) 1.15 (0.91–1.44) 1.13 (0.90–1.43)
15–19.9 17,558 11 0.12 0.92 (0.50–1.68) 0.92 (0.50–1.68) 0.87 (0.47–1.58) 0.86 (0.47–1.57)
20- 2925 5 0.34 2.60 (1.07–6.30) 2.56 (1.06–6.21) 2.37 (0.98–5.74) 2.39 (0.99–5.80)
  1. Model 1: crude model; Model 2: adjusting for sex, smoking status, alcohol history, exercise level, and income; Model 3: adjusting for variables of Model 2 with BMI, DM, HT, dyslipidemia, and eGFR; Model 4: adjusting for variables of Model 3 and state of dipstick proteinuria (4 categories)
  2. BMI body mass index, CKD-EPI Chronic Kidney Disease Epidemiology Collaboration equation based on serum creatinine, DM diabetes mellitus, eGFR estimated glomerular filtration rate, ESRD end-stage renal disease, HT hypertension, TUG timed up-and-go test
  3. aPer 1000 person-years