Table 2 Comparison between controls and ADPKD patients with stage 3 CKD

Age (years)

53.69 ± 11.63

54.54 ± 11.73

NS

Male gender

262 (52.5%)

30 (52.6%)

NS

Hypertension

163 (32.7%)

52 (91.2%)

< 0.001

Dyslipidemia

157 (31.5%)

37 (64.9%)

< 0.001

Creatinine (mg/dL)

0.84 ± 0.15

1.69 ± 0.35

< 0.001

eGFR (mL/min/1.73m²)

91.82 ± 16.94

41.13 ± 8.52

< 0.001

Macroalbuminuria

0 (0.0%)

5 (13.2%)

< 0.001

Total cholesterol (mg/dL)

204.41 ± 35.63

187.42 ± 40.68

0.001

HDL-cholesterol (mg/dL)

54.36 ± 15.38

49.05 ± 12.37

0.020

LDL-cholesterol (mg/dL)

128.73 ± 32.74

111.12 ± 31.93

< 0.001

Triglycerides (mg/dL)

112.32 ± 66.08

132.82 ± 64.99

0.030

Hemoglobin (g/dL)

14.54 ± 1.41

13.56 ± 1.35

< 0.001

Albumin (g/dL)

4.36 ± 0.30

4.23 ± 0.32

0.008

Uric acid (mg/dL)

5.05 ± 1.45

6.80 ± 1.28

< 0.001

iPTH (pg/mL)

53.54 ± 15.34

96.79 ± 46.94

< 0.001

Potassium (mEq/L)

4.47 ± 0.40

4.61 ± 0.45

0.017

DBP (mmHg)

79.84 ± 9.66

83.53 ± 9.35

0.006

Overweight (BMI 25.1–30 Kg/m²)

236 (47.3%)

23 (46.9%)

< 0.001

Target LDL-cholesterol

349 (80.4%)

23 (46.9%)

< 0.001

Cardiovascular event

11 (2.2%)

0 (0.0%)

NS

Cardiovascular death

0 (0.0%)

0 (0.0%)

–

Non cardiovascular death

3 (0.6%)

1 (1.8%)

NS