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Table 2 Cox regression analysis for composite outcome of all-cause mortality and graft loss

From: C-terminal and intact FGF23 in kidney transplant recipients and their associations with overall graft survival

Variable

Composite outcome

HR (95% CI)

P

Log C-terminal FGF23

 Univariate analysis

1.46 (1.31–1.63)

< 0.001

 Model 1

1.23 (1.07–1.42)

0.005

 Model 2

1.28 (1.09–1.50)

0.003

 Model 3

1.35 (1.03–1.76)

0.029

 Model 4

1.37 (1.03, 1.81)

0.030

 Model 5

1.33 (1.01, 1.75)

0.040

 Model 6

1.35 (1.01, 1.79)

0.043

Log intact FGF23

 Univariate analysis

1.28 (1.14–1.44)

< 0.001

 Model 1

1.05 (0.92–1.21)

0.473

 Model 2

1.06 (0.92–1.23)

0.425

 Model 3

1.03 (0.81–1.31)

0.833

 Model 4

0.99 (0.77, 1.28)

0.936

 Model 5

0.99 (0.77, 1.26)

0.920

 Model 6

0.97 (0.75, 1.25)

0.794

  1. Model 1: eGFR; Model 2: eGFR, gender, age; Model 3: eGFR, gender, age, time post-transplantation, hemoglobin, albumin, donor’s age, cold ischemia time, log serum calcium, log serum phosphorus, log parathyroid hormone, urinary protein excretion; Model 4: model 3 + CRP; Model 5: model 3 + MCV + ferritin; Model 6: model 3 + CRP + MCV + ferritin
  2. HR hazard ratio, 95%CI 95% confidence interval, eGFR estimated glomerular filtration rate, CRP C-reactive protein, MCV mean corpuscular volume