Skip to main content

Table 4 Expression of PLA2R and IgG4 in different stages of MN according to pathologic stage

From: A cohort study of membranous nephropathy, primary or secondary

   Mild (n = 19)
(stage I)
Moderate (n = 80)
(stage II)
Severe (n = 9)
(stage III-IV)
p value
PLA2R Positive 14 (73.7%) 60 (75%) 3 (33.3%) 0.03
Negative 5 (26.3%) 20 (20%) 6 (67.7%)  
Staining intensity Moderate 6 (42.9%) 23 (38.3%) - 0.37
severe 8 (57.1%) 37 (61.7%) 3 (100%)  
IgG4 Positive 12 (63.2%) 56 (70%) 3 (33.3%) 0.08
Negative 7 (36.8%) 24 (24%) 6 (67.7%)  
  1. Abbreviations: MN membranous nephropathy, PLA2R phospholipase A2 receptor, IgG4 Immunoglobulin G4
\