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Table 4 Expression of PLA2R and IgG4 in different stages of MN according to pathologic stage

From: A cohort study of membranous nephropathy, primary or secondary

Ā Ā 

Mild (n = 19)

(stage I)

Moderate (n = 80)

(stage II)

Severe (n = 9)

(stage III-IV)

p value

PLA2R

Positive

14 (73.7%)

60 (75%)

3 (33.3%)

0.03

Negative

5 (26.3%)

20 (20%)

6 (67.7%)

Ā 

Staining intensity

Moderate

6 (42.9%)

23 (38.3%)

-

0.37

severe

8 (57.1%)

37 (61.7%)

3 (100%)

Ā 

IgG4

Positive

12 (63.2%)

56 (70%)

3 (33.3%)

0.08

Negative

7 (36.8%)

24 (24%)

6 (67.7%)

Ā 
  1. Abbreviations: MN membranous nephropathy, PLA2R phospholipase A2 receptor, IgG4 Immunoglobulin G4