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Table 3 Induction regimens and proteinuria remission rate of iMN and aMN patients

From: Renal outcomes of idiopathic and atypical membranous nephropathy in adult Chinese patients: a single center retrospective cohort study

 

iMN group (n = 99)

aMN group (n = 105)

p value

Induction regimens

  

0.284

Supportive care only

6(6.1 %)

10(9.5 %)

 

GC + CTX

80(80.8 %)

77(73.3 %)

 

GC + CNIs

6(6.1 %)

13(12.4 %)

 

Other ISTs

7(7.0 %)

5(4.8 %)

 

Proteinuria remission rates at 6th month

24hUPE(g/24 h)

1.62(0.58,6.00)

2.60(1.15,6.23)

0.823

Complete remission

18/88(20.5 %)

10/98(10.2 %)

0.051

Overall remission

52/88(59.1 %)

51/98(52.0 %)

0.334

Proteinuria remission rates at endpoint

24hUPE(g/24 h)

0.23(0.10,2.67)

0.75(0.14,3.74)

0.098

Complete remission

54(54.5 %)

45(42.9 %)

0.095

Overall remission

73(73.7 %)

73(69.5 %)

0.505

Renal outcomes

ESRD

7(7.1 %)

4(3.8 %)

0.303

primary outcomea

25(25.3 %)

21(20.0 %)

0.370

  1. GC glucocorticoid; CTX cyclophosphamide; CNI calcineurin inhibitor; IST immunosuppressive therapy; 24hUPE 24 h urinary protein excretion; ESRD end-stage renal disease. aPrimary outcome was worsening of the renal function, defined as a 30 % or more decrease in eGFR or ESRD (eGFR < 15ml/min/1.73m2)