Table 1 Anthropometric and laboratory characteristics of healthy individuals and patients with PNS
Variables | PNS n = 133 | Controls n = 60 | P value |
|---|---|---|---|
Sex (F/M) | 94 / 39 | 40 / 20 | 0.576 |
Age (years) | 33.23 ± 20.16 | 36.05 ± 16.40 | 0.276 |
BMI (kg/m2) | 22.94 ± 2.78 | 22.24 ± 1.75 | 0.051 |
SBP (mmHg) | 120.00 (107.50, 129.00) | 117.00 (108.25, 126.75) | 0.466 |
DBP (mmHg) | 73.39 ± 10.03 | 73.50 ± 8.32 | 0.941 |
CHOL (mmol/L) | 8.25 (6.42, 10.33) | 4.39 (3.74, 4.95) | < 0.001* |
TG (mmol/L) | 2.77 (1.91, 3.29) | 1.11 (0.96, 1.43) | < 0.001* |
HDL-C (mmol/L) | 1.66 (1.25, 1.98) | 1.31 (1.19, 1.48) | < 0.001* |
LDL-C (mmol/L) | 5.11 (3.61, 6.64) | 2.51 (2.13, 2.91) | < 0.001* |
ALB (g/L) | 23.40 (17.90, 28.95) | 46.25 (44.13, 47.96) | < 0.001* |
CREA (μmol/L) | 62.50 (46.60, 78.10) | 58.65 (50.13, 76.15) | 0.891 |
Ur (mmol/L) | 6.10 (4.50, 8.30) | 4.26 (3.67, 5.39) | < 0.001* |
Urine protein | 1 ~ 4 | ngegative | < 0.001* |
24hUTP (g/d) | 5.989 (2.297, 9.140) | – | |
Serum ANGPTL8 (ng/ml)a | 28.29 (22.31, 31.30) | 23.21 (19.55, 25.11) | < 0.001* |
Urine ANGPTL8 (ng/ml)a | 42.36 (37.45, 76.44) | 36.38 (33.59, 39.41) | < 0.001* |