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Table 1 Example case vignette. Age, serum calcium, and PTH were varied for the eight clinical case vignettes

From: Practice variation in the treatment of patients with renal hyperparathyroidism: a survey-based study in the Netherlands

40-year old male

Currently on hemodialysis for 1.5 years, being screened for kidney transplantation in order to receive a donor kidney from his brother.

Serum PTH and calcium: 40 pmol/L (ref: 0.7–8 pmol/L) and 2.25 mmol/L (ref: 2.15–2.55 mmol/L) respectively.

25 (OH) Vitamin D and plasma phosphate are 100 nmol/L (ref: >  50 nmol/L) and 1.4 mmol/L (ref: 0.9–1.5 pmol/L) respectively, optimized by vitamin D supplementation and phosphate binders.

What would be your treatment of choice for this patient?

Maintain conservative treatment

Start calcimimetic treatment

Opt for subtotal parathyroidectomy