Association between baseline LDL-C and prognosis among patients with coronary artery disease and advanced kidney disease

Table 3 Subgroup analysis of LDL-C level with mortality among CAD and CKD patients

Subgroup	No of events / No of patients		Multivariate Cox Regression				P for interaction
Subgroup	LDL-C < 1.8	LDL-C ≥ 1.8	HR	95% CI		P value	P for interaction
On dialysis
Yes	39/67 (58.2%)	86/216 (39.8%)	1.66	1.03	2.68	0.04	0.38
No	36/71 (50.7%)	154/449 (34.3%)	1.22	0.79	1.88	0.38	0.38
ACS
Yes	31/58 (53.4%)	120/328 (36.6%)	1.36	0.84	2.19	0.21	0.76
No	44/80 (55.0%)	120/337 (35.6%)	1.33	0.87	2.02	0.18	0.76
DM
Yes	48/86 (55.8%)	129/343 (37.6%)	1.59	1.05	2.40	0.03	0.35
No	27/52 (51.9%)	111/322 (34.5%)	1.30	0.78	2.18	0.32	0.35

Abbreviations: ACS Acute coronary syndrome; DM Diabetes mellitus
Adjusted for full multivariate variables: age, male, current smoker, ACS, CHF, hypertension, DM, dialysis, anemia, PAD, 15 ≤ eGFR < 30 ml/min/1.73 m² vs. eGFR < 15 ml/min/1.73 m², previous AMI, PCI, WBC, albumin, total Cholesterol, triglyceride, high-density lipoprotein cholesterol, Lg ProBNP, Lg D-dimer, ACEI/ARB, β-blockers, statins, diuretics

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