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Table 4 Performance statistics for the one-sample method of Fleming. The reference GFR was obtained with the S-NLLS-method on n = 541 subjects

From: Iohexol plasma clearance for measuring glomerular filtration rate: effect of different ways to calculate the area under the curve

Statistics Time-point (minutes after injection)
120 150 180 240 300
LIN’s CCC 0.865 0.868 0.857 0.839 0.832
RMSE 9.18 8.90 9.20 9.78 9.98
Bias [95% CI] −0.95 [−1.72;-0.18] −2.12 [−2.85;-1.39] − 2.97 [− 3.70;-2.23] −4.05 [− 4.80;-3.30] −4.21 [− 4.97;-3.44]
SD 9.1 8.7 8.7 8.9 9.1