Table 2 Etiology of CKD in childhood population during 2013~2016

No. of patients (%)

Total

2013

2014

2015

2016

Glomerular disease

73,806 (21.18 %)

21,077 (24.89 %)

22,195(23.31 %)

23,117(23.00 %)

21,469(20.93 %)

 Hereditary glomerular disease

2502 (0.72 %)

615 (0.73 %)

619(0.65 %)

825(0.82 %)

845(0.82 %)

 Congenital glomerular disease

418 (0.12 %)

96 (0.11 %)

111(0.12 %)

127(0.13 %)

106(0.10 %)

 Primary glomerular disease

70,886 (20.34 %)

20,366 (24.05 %)

21,465(22.54 %)

22,165(22.05 %)

20,518(20.01 %)

Tubular and tubular interstitial diseases

9717 (2.79 %)

2376 (2.81 %)

2595(2.73 %)

2747(2.74 %)

2764(2.70 %)

 Hereditary/congenital renal tubular disease

3758 (1.08 %)

979 (1.16 %)

1047(1.1 %)

1045(1.04 %)

1119(1.09 %)

 Primary renal tubular disease

224 (0.06 %)

50 (0.06 %)

63(0.07 %)

67(0.07 %)

48(0.05 %)

 Renal tubular interstitial disease

5735 (1.65 %)

1347 (1.59 %)

1485(1.56 %)

1635(1.63 %)

1597(1.56 %)

Secondary nephrosis

132,305 (37.95 %)

31,765 (37.50 %)

35,758(37.56 %)

37,265(37.09 %)

39,482(43.94 %)

 HSPN

31,167 (8.94 %)

8278 (9.77 %)

8438(8.86 %)

8006(7.97 %)

8606(8.39 %)

 LN

6701 (1.92 %)

2050 (2.42 %)

2229(2.34 %)

2342(2.33 %)

2353(2.29 %)

 HUS

593 (0.17 %)

158 (0.19 %)

149(0.16 %)

183(0.18 %)

174(0.17 %)

Other nephrosis

93,844 (26.92 %)

21,279 (25.13 %)

24,942 (26.19 %)

26,734 (26.6 %)

28,349 (27.65 %)

 Renal injury related to autoimmune and connective tissue diseases

56,346 (16.14 %)

14,145 (16.70 %)

15,684 (16.47 %)

15,821 (15.74 %)

16,199 (15.80 %)

 Renal injury related to metabolic disorders

33,064 (9.49 %)

6061 (7.16 %)

8022(8.43 %)

9634(9.59 %)

11,000(10.73 %)

No. of patients (%)

合计

2013

2014

2015

2016

Renal injury related to infectious disorders

1212 (0.35 %)

314 (0.37 %)

337(0.35 %)

319(0.32 %)

289(0.28 %)

Renal injury related to drugs

196 (0.06 %)

49 (0.06 %)

49(0.05 %)

56(0.06 %)

43(0.04 %)

Renal vascular thrombosis and embolism

233 (0.07 %)

79 (0.09 %)

56(0.06 %)

50(0.05 %)

49(0.05 %)

Thrombotic microangiopathy

197 (0.06 %)

145 (0.17 %)

22(0.02 %)

11(0.01 %)

20(0.02 %)

Antiphospholipid syndrome

128 (0.04 %)

41 (0.05 %)

25(0.03 %)

34(0.03 %)

34(0.03 %)

Hypertensive renal damage

2468 (0.71 %)

445 (0.53 %)

747(0.78 %)

809(0.80 %)

715(0.70 %)

CAKUT

85,745 (24.61 %)

18,360 (21.68 %)

22,297(23.41 %)

23,974(23.85 %)

25,310(24.68 %)

Renal hypoplasia, dysplasia, oligonephronia

37,137 (10.66 %)

7547 (8.91 %)

9239(9.7 %)

10,013(9.96 %)

11,640(11.35 %)

Obstructive and recurrent urinary tract disease

48,608 (13.95 %)

10,813 (12.77 %)

13,058(13.71 %)

13,960(13.89 %)

13,670(13.33 %)

Cystic kidney disease

17,668 (5.07 %)

3811 (4.50 %)

4584(4.81 %)

5329(5.3 %)

5339(5.21 %)

Renal injury related to tumors

4091 (1.17 %)

1120 (1.32 %)

1218(1.28 %)

1321(1.31 %)

1269(1.24 %)

CRF with unknown reason

14,485 (4.16 %)

3780 (4.46 %)

3771(3.96 %)

3864(3.84 %)

4120(4.02 %)

Others

10,699 (3.07)

2404 (2.84 %)

2796(2.94 %)

2883(2.87 %)

2787(2.72 %)