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Table 1 Demographic and clinical characteristics of the study population with AF at baseline according to ischemic stroke event

From: Prior ischemic strokes are non-inferior for predicting future ischemic strokes than CHA2DS2-VASc score in hemodialysis patients with non-valvular atrial fibrillation

Variables

Without Stroke

(n = 222)

With Stroke

(n = 46)

P value

Age (y)

73.4 ± 10.5

73.2 ± 8.8

0.89

Gender male n (%)

86 (39)

19 (41)

0.74

DM n (%)

150 (68)

35 (76)

0.30

Dialysis vintage (years)

0.0 (0.0–3.0)

0.0 (0.0–2.0)

0.66

Kt/V

1.34 ± 0.18

1.41 ± 0.18

0.02

Vascular access

  

0.70

 Arterio-venous fistula n (%)

78 (35)

21 (46)

 

 Arterio-venous graft n (%)

16 (7)

4 (9)

 

 Central venous Catheter n (%)

128 (58)

21 (46)

 

Heparin dose during HD session (units)

2500 (1250–2500)

2500 (0–2500)

0.28

Comorbidity index

8.7 ± 3.3

9.1 ± 2.9

0.44

Functional status (need in nursing care) n (%)

120 (55)

28 (61)

0.41

Dementia n (%)

36 (16)

10 (22)

0.39

A-V access thrombosis n (%)

42 (19)

15 (33)

0.06

Left atrium size (cm)

4.3 ± 0.7

4.4 ± 0.5

0.94

Time since AF diagnosis (years)

3.0 (1.0–7.0)

4.0 (1.0–7.8)

0.45

All-cause death n (%)

175 (79)

41 (89)

0.15

Warfarin use n (%)

76 (34)

15 (33)

0.87

Aspirin use n (%)

126 (57)

27 (59)

0.86

Clopidogrel use n (%)

45 (20)

15 (33)

0.29

Dual antiplatelet therapy n (%)

33 (15)

7 (15)

0.96

Enoxaparin use n (%)

29 (13)

6 (13)

0.97

INR

1.2 (1.1–1.5)

1.2 (1.1–1.5)

0.95

Hb (g/dL)

10.0 ± 1.8

10.6 ± 1.5

0.12

Platelets(× 103/mm3)

191.1 ± 70.3

216.4 ± 80.1

0.27

Mean CHA2DS2-VASc score

4.9 ± 1.6

5.7 ± 1.6

0.005

CHA2DS2-VASc score

  

0.06

 0 n (%)

1 (0.5)

0 (0)

 

 1 n (%)

5 (2.3)

0 (0)

 

 2 n (%)

11 (4.9)

1 (2.2)

 

 3 n (%)

20 (9.0)

4 (8.7)

 

 4 n (%)

44 (19.8)

6 (13.0)

 

 5 n (%)

64 (28.8)

7 (15.2)

 

 6 n (%)

40 (18.0)

16 (34.8)

 

 7 n (%)

25 (11.3)

5 (10.9)

 

 8 n (%)

10 (4.5)

5 (10.9)

 

 9 n (%)

2 (0.9)

2 (4.3)

 
  1. Continuous variables with normal distribution are expressed as means (SDs), as medians (interquartile ranges) for non–normally distributed data, and categorical variables are expressed as percentages
  2. Abbreviations: AF atrial fibrillation, HD hemodialysis, DM diabetes mellitus, GI gastrointestinal, PPI proton pump inhibitor, Hb hemoglobin