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Table 4 Comparison of the CHA2DS2-VASc score and prior stroke and/or TIA in predicting of ischemic stroke according to multivariable Cox proportional hazard models in the study population

From: Prior ischemic strokes are non-inferior for predicting future ischemic strokes than CHA2DS2-VASc score in hemodialysis patients with non-valvular atrial fibrillation

Variable

All patients (n = 268)

Without warfarin (n = 180)

HR

95% CI

P value

HR

95% CI

P value

CHA2DS2-VASc score (↑ per unit)

Crude

  CHA2DS2-VASc

1.28

1.08–1.53

0.006

1.11

0.90–1.37

0.32

Multivariable models

  1. Crude +Hb + Co-morbidity index

1.66

1.22–2.28

0.001

1.32

0.90–1.92

0.16

  2. 1 + Time since AF diagnosis + Kt/V + A-V access thrombosis in the past

1.73

1.23–2.45

0.002

1.22

0.81–1.85

0.34

  3. 2 + All-cause death

1.74

1.23–2.46

0.002

1.22

0.81–1.84

0.35

CHA2DS2-VASc score (≥6)

Crude

  CHA2DS2-VASc

2.75

1.43–5.31

0.003

2.61

1.14–5.94

0.02

Multivariable models

  1. Crude + Hb + Co-morbidity index

5.81

2.04–16.60

0.001

6.03

1.51–24.05

0.01

  2. 1 + Time since AF diagnosis + Kt/V + A-V access thrombosis in the past

5.56

1.89–16.36

0.002

4.92

1.09–22.22

0.04

  3. 2 + All-cause death

5.57

1.88–16.49

0.002

5.00

1.09–22.88

0.04

Prior stroke and/or TIA

Crude

  prior stroke and/or TIA (yes)

3.44

1.78–6.65

< 0.001

2.63

1.56–5.97

0.02

Multivariable models

  1. Crude +Hb + Co-morbidity index

8.55

2.93–24.97

< 0.001

8.86

1.95–40.36

0.005

  2. 1 + Time since AF diagnosis + Kt/V + A-V access thrombosis in the past

8.64

2.83–26.36

< 0.001

8.21

1.64–40.95

0.01

  3. 2 + All-cause death

8.65

2.82–26.49

< 0.001

8.23

1.65–41.16

0.01

  1. Abbreviations: Hb hemoglobin, AF atrial fibrillation, TIA transient ischemic attack