Variable | HR | 95% CI | P value |
---|---|---|---|
HAS-BLED score | |||
Crude | |||
HAS-BLED (↑ per unit) | 0.89 | 0.63–1.27 | 0.53 |
Multivariable models | |||
1. Crude + INR | 0.80 | 0.54–1.19 | 0.27 |
2. 1 + Comorbidity index + Functional status | 0.70 | 0.44–1.12 | 0.19 |
3. 2 + Dual antiplatelet therapy + Kt/V + PPI use | 0.76 | 0.47–1.20 | 0.24 |
4. 3 + All-cause death | 0.76 | 0.48–1.22 | 0.25 |
Prior Major Bleeding | |||
Crude | |||
Prior Major Bleeding (yes) | 2.30 | 1.00–5.27 | 0.05 |
Multivariable models | |||
1. Crude + INR | 1.65 | 0.62–4.24 | 0.30 |
2. 1 + Comorbidity index + Functional status | 2.05 | 0.63–6.72 | 0.23 |
3. 2 + Dual antiplatelet therapy + Kt/V + PPI use | 2.10 | 0.67–6.59 | 0.20 |
4. 3 + All-cause death | 2.07 | 0.62–6.92 | 0.24 |