Fig. 3From: Metabolic acidosis is associated with increased risk of adverse kidney outcomes and mortality in patients with non-dialysis dependent chronic kidney disease: an observational cohort studyTwo-year incidence of the composite outcome of DD40 by CKD stage (unadjusted analysis). The analysis included patients from the extended cohort: metabolic acidosis group, N = 17,350; normal serum bicarbonate group, N = 34,208). Abbreviations: CKD, chronic kidney disease; DD40, ≥ 40 % eGFR decline, renal replacement therapy, or all-cause mortality. *P < 0.001, **P < 0.05, metabolic acidosis group vs. normal serum bicarbonate groupBack to article page