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Table 3 The association of the percentage change in estimated GFR per year (%ΔeGFR/y) and the percentage change in measured GFR per year (%ΔmGFR/y) on different clinical parameters

From: The correlation between kidney volume and measured glomerular filtration rate in an Asian ADPKD population: a prospective cohort study

Clinical parameters

(N = 32)

%ΔeGFR/y

%ΔmGFR/y

Univariate analysis

Univariate analysis

Multivariate analysis

r

95 % CI

p

r

95 % CI

p

r

95 % CI

p

Age (year)

–0.082

0.173 to 0.111

0.656

0.100

–0.165 to 0.095

0.587

   

BMI (Kg/m2)

–0.194

–0.863 to 0.266

0.288

0.137

–0.715 to 0.328

0.454

   

Mean SBP (mmHg)

0.093

–0.088 to 0.146

0.612

0.148

–0.149 to 0.064

0.418

   

Mean DBP (mmHg)

0.052

–0.179 to 0.236

0.778

0.131

–0.255 to 0.122

0.476

   

Initial eGFR (mL/min/1.73 m2)

0.385

0.008 to 0.142

0.030*

-

-

-

   

Initial mGFR (mL/min/1.73 m2)

-

-

-

0.476

0.025 to 0.137

0.006*

0.265

–0.013 to 0.103

0.123

Initial htTKV (mL/m)

0.126

–0.002 to 0.005

0.493

0.282

–0.006 to 0.001

0.117

   

24-hr urine protein (mg/day/1.73 m2)

–0.301

–0.018 to 0.002

0.094

0.419

–0.019 to –0.002

0.017*

0.038

–0.012 to 0.014

0.881

24-hr urine albumin (mg/day/1.73 m2)

–0.205

–0.025 to 0.007

0.261

0.497

–0.033 to –0.007

0.004*

0.357

0.027 to 0.001

0.034*

%ΔhtTKV/y (%/year)

–0.254

–0.767 to 0.133

0.161

0.501

–0.941 to –0.203

0.004*

0.363

0.791 to 0.039

0.032*

  1. * indicates statistical significance (P < 0.05)
  2. %ΔeGFR/y percentage change in estimated GFR per year, %ΔmGFR/y percentage change in measured GFR per year; BMI body mass index; SBP systolic blood pressure; DBP diastolic blood pressure; htTKV height-adjusted total kidney volume; %ΔhtTKV/y percentage change in height-adjusted total kidney volume per year