Table 1 Comparison of clinical characteristics and laboratory data between the osteoporosis and non-osteoporosis groups in patients on HD

Number

339

98

241

General data

  Age(years)

56.79 ± 15.60

66.45 ± 13.28

52.86 ± 14.77

  Sex(male %)

193(56.93 %)

60(61.22 %)

133(55.19 %)

  Dialysis vintage(years)

4.33 ± 4.91

4.63 ± 4.87

4.21 ± 4.94

  Body mass index(BMI)

22.99 ± 4.01

22.93 ± 4.03

23.01 ± 4.01

  Systolic BP(mmHg)

145.78 ± 24.40

145.94 ± 24.37

145.72 ± 24.46

  Diastolic BP(mmHg)

82.32 ± 14.60

78.51 ± 14.55

83.87 ± 14.36

Blood data

  Hemoglobin(g/L)

97.57 ± 20.14

98.47 ± 20.94

97.20 ± 19.84

  Albumin(g/L)

35.89 ± 6.13

35.36 ± 6.41

36.11 ± 6.02

  Uric acid(mmol/L)

378.64 ± 125.83

368.83 ± 120.70

382.63 ± 127.89

  Triglycerides(mmol/L)

1.81 ± 1.37

1.75 ± 1.45

1.84 ± 1.33

  Total cholesterol(mmol/L)

4.13 ± 1.12

4.06 ± 1.00

4.16 ± 1.17

  Dicarbonate(mmol/L)

22.65 ± 3.76

22.63 ± 3.87

22.66 ± 3.72

  Calcium(mmol/L)

2.26 ± 0.24

2.28 ± 0.25

2.26 ± 0.24

  Phosphate(mmol/L)

1.70(0.19,4.16)

1.69(0.28,4.16)

1.76(0.19,3.35)

  Parathormon(pg/ml)

374.07 ± 418.87

347.02 ± 385.80

385.07 ± 431.87

  FGF21 quartiles (pg/ml)

386.67

930.23

288.80

  FGF23 quartiles (pg/ml)9309.83 ± 10410.899529.83 ± 9485.399220.37 ± 10782.060.804

13116.71

16210.65

13189.01

Comorbidity

  Diabetes(%)

112(33.04 %)

45(45.92 %)

67(27.80 %)

  Hypertension(%)

298(87.91 %)

87(88.78 %)

211(87.55 %)

  CVD(%)

94(27.73 %)

48(48.98 %)

46(19.09 %)

Medicine usage

  Vitamin D(%)

151(44.54 %)

31(31.63 %)

120(49.79 %)

  Calciu supplements(%)

86(25.37 %)

22(22.45 %)

64(26.56 %)

  Cinacalcet(%)

52(15.34 %)

11(11.22 %)

41(17.01 %)

  ACEI/ARB(%)

94(27.73 %)

28(28.57 %)

66(27.39 %)

FRAX(306) ^a

  Major Osteoporosis

3(0.9,14)

4.0(1.0,13.0)

2.55(0.9,14)

  Hip fracture

0.8(0.0,10.0)

1.95(0,10)

0.5(0,10)