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Table 3 Receiver operator characteristic (ROC) analysis of proteinuria in first and second morning spot urine collections

From: First and second morning spot urine protein measurements for the assessment of proteinuria: a diagnostic accuracy study in kidney transplant recipients

24-h proteinuria (mg/day/1.73m2)

Urine sample

PCR / ePER cutoff point

(mg/mmol / mg/day/1.73m2)

Area under the ROC curve (95% CI)

Sensitivity of PCR/ePER % (95% CI)

Specificity of PCR/ePER % (95% CI)

> 150

first morning

27 / 235

0.89 (0.82 to 0.96)

83 (74 to 89)

86 (77 to 92)

second morning

26 / 225

0.92 (0.86 to 0.98)

83 (74 to 89)

86 (77 to 92)

> 300

first morning

39 / 345

0.92 (0.88 to 0.96)

84 (75 to 90)

86 (77 to 92)

second morning

38 / 335

0.96 (0.93 to 0.99)

88 (80 to 93)

89 (81 to 94)

> 1000

first morning

107 / 940

0.98 (0.97 to 0.99)

93 (83 to 98)

96 (89 to 99)

second morning

105 / 925

0.98 (0.97 to 0.99)

89 (81 to 94)

96 (89 to 99)

  1. Abbreviations: PCR protein-to-creatinine ratio, ePER estimated protein excretion rate, CI confidence interval