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Table 1 Characteristics of participants according to the SNP rs35767 genotypea

From: Association between polymorphism at IGF-1 rs35767 gene locus and long-term decline in renal function: a Japanese retrospective longitudinal cohort study

  Genotype
CC TC TT P
Sex (Female/Male) 101/549 83/604 22/147 0.17
Age (years) 33.8 ± 9.4 34.0 ± 9.3 33.8 ± 8.7 0.89
BMI (kg/m2) 22.9 ± 3.6 22.9 ± 3.5 22.7 ± 3.2 0.76
SBP (mmHg) 126.6 ± 17.1 127.6 ± 16.5 126.2 ± 17.5 0.42
DBP (mmHg) 76.6 ± 11.8 77.6 ± 11.4 76.2 ± 12.2 0.22
MBP (mmHg) 93.28 ± 12.5 94.2 ± 12.1 92.9 ± 13.2 0.25
AST (IU/L) 22.9 ± 11.4 23.5 ± 11.3 23.4 ± 10.1 0.68
ALT (IU/L) 26.1 ± 21.6 26.4 ± 19.9 25.2 ± 17.9 0.67
Cr (mg/dL) 0.77 ± 0.18 0.77 ± 0.23 0.78 ± 0.28 0.87
eGFR (mL/min/1.73m2) 96.8 ± 19.8 96.8 ± 20.1 98.3 ± 19.4 0.65
UA (mg/dL) 5.8 ± 1.4 5.8 ± 1.4 5.9 ± 1.4 0.81
TC (mg/dL) 195.1 ± 33.1 194.8 ± 32.9 193.6 ± 31.8 0.27
HDLC (mg/dL) 65.8 ± 16.3 66.0 ± 16.1 64.9 ± 15.3 0.83
LDLC (mg/dL) 116.0 ± 31.6 112.6 ± 30.0 112.4 ± 28.1 0.10
TG (mg/dL) 104.1 ± 80.2 106.9 ± 82.8 99.9 ± 81.9 0.27
HbA1c (%) 5.32 ± 0.59 5.32 ± 0.68 5.20 ± 0.45 0.07
  1. an = 1506
  2. Data are presented as the mean ± standard deviation
  3. Abbreviations: SNP single-nucleotide polymorphism, IGF-1 insulin-like growth factor-1, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, MBP mean blood pressure, AST aspartate transaminase, ALT alanine transaminase, Cr creatinine, eGFR estimated glomerular filtration rate, UA uric acid, TC total cholesterol, HDLC high-density lipoprotein cholesterol, LDLC low-density lipoprotein cholesterol, TG triglyceride, HbA1c glycated hemoglobin