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Table 3 Association of rs35767 genotype with HbA1c, UA, and eGFR according to sex

From: Association between polymorphism at IGF-1 rs35767 gene locus and long-term decline in renal function: a Japanese retrospective longitudinal cohort study

  HbA1c UA eGFR
Model 1(M) 2(F) 3(All) 1(M) 2(F) 3(All) 1(M) 2(F) 3(All)
  β (SE) p β (SE) p β
(SE)
p β
(SE)
p β
(SE)
p β
(SE)
p β
(SE)
p β
(SE)
p β
(SE)
p
CC Ref   Ref   Ref   Ref   Ref   Ref   Ref   Ref   Ref  
TC −0.01 (0.02) 0.89 0.01 (0.05) 0.95 − 0.01 (0.02) 0.86 −0.03 (0.07) 0.65 0.02 (0.12) 0.89 0.03 (0.06) 0.61 0.19 (0.86) 0.83 1.67 (3.00) 0.58 0.29 (0.86) 0.73
TT −0.05 (0.03) 0.13 −0.09 (0.07) 0.19 −0.06 (0.03) 0.05 0.05 (0.10) 0.61 0.04 (0.19) 0.81 0.10 (0.10) 0.32 1.99 (1.35) 0.14 1.70 (4.71) 0.72 2.06 (1.35) 0.12
  1. Model 1, males only (M); Model 2, females only (F); Model 3, males and females (All); all models adjusted for age, BMI, MBP, eGFR, UA, LDLC, HbA1c
  2. n = 1506 (F/M, 206/1300)
  3. Abbreviations: HbA1c glycated hemoglobin, UA uric acid, eGFR estimated glomerular filtration rate, BMI body mass index, LDLC low-density lipoprotein cholesterol, MBP mean blood pressure, β regression coefficients, ref. reference, SE standard error