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Table 3 Comparison of graft and patient outcome after either simultaneous heart-kidney or solitary kidney transplantation

From: Simultaneous heart-kidney transplantation results in respectable long-term outcome but a high rate of early kidney graft loss in high-risk recipients – a European single center analysis

Variables

HKTx

KTx

p-value

Mean; Median (Range)

N (%)

M. v.

Mean; Median (Range)

N (%)

M. v.

Outcome

1-month eGFR (in ml/min)

61.20; 53.43 (25.13-118.89)

 

11 (40.7)

44.23; 42.07 (10.23-92.15)

 

1 (3.7)

0.066

3-month eGFR (in ml/min)

49.98; 51.64 (23.07-72.98)

 

9 (33.3)

46.60; 44.83 (19.44-97.48)

 

2 (7.4)

0.584

6-month eGFR (in ml/min)

45.87; 42.27 (18.81-91.41)

 

7 (25.9)

49.38; 42.22 (16.38-105.52)

 

2 (7.4)

0.571

1-year eGFR (in ml/min)

46.19; 45.01 (13.60-82.95)

 

7 (25.9)

51.53; 49.09 (21.25-80.24)

 

3 (11.1)

0.358

2-year eGFR (in ml/min)

44.58; 42.15 (14.75-79.89)

 

8 (29.6)

49.44; 47.22 (22.13-77.70)

 

4 (14.8)

0.360

3-year eGFR (in ml/min)

44.24; 36.99 (12.48-85.31)

 

8 (29.6)

47.34; 47.79 (27.29-78.49)

 

3 (11.1)

0.584

5-year eGFR (in ml/min)

43.59; 37.73 (19.92-93.55)

 

12 (44.4)

47.82; 43.15 (21.28-90.58)

 

5 (18.5)

0.421

10-year eGFR (in ml/min)

46.11; 48.59 (15.98-77.03)

 

18 (66.7)

49.18; 41.46 (30.13-88.25)

 

16 (59.3)

0.732

Subsequent dialysis

 

13 (48.1)

0 (0)

 

6 (22.2)

0 (0)

0.044

ICU stay (in days)

15.62; 5.5 (1-89)

 

1 (3.7)

2.07; 1 (0-8)

 

<0.001

Hospital stay (in days)

56.78; 27 (14-236)

 

0 (0)

21.59; 20 (8-56)

 

0.022

Surgical complications

 

13 (48.1)

 

4 (14.8)

0.008

Primary nonfunction (renal graft)

 

5 (18.5)

 

0 (0)

0.051

In-hospital mortality

 

6 (22.2)

 

0 (0)

0.023

  1. HKTx: simultaneous heart and kidney transplantation; KTx: kidney transplantation; HTx: heart transplantation; eGFR: estimated glomerular filtration rate; ICU: intensive care unit; M.v.: missing values. Bold values indicate statistical significance.