Processing speed is affected by early impairment in kidney function in the general elder population

BMC Nephrology

Table 2 Incidence of dementia, MCI and MCI subtypes at follow up based on kidney function at baseline

Outcome	Number of incidents from baseline to follow up (cumulative incidence in % in parenthesis)			OR^a (95 % CI for OR) p–value
Outcome	All participants (n=905)	Participants with eGFR < 60 mL/min/1,73 m2 from baseline to follow up (n=196)	Participants with eGFR ≥ 60 mL/min/1,73 m2 from baseline to follow up (n=709)	All participants (n=905)
Dementia	14 (1.5 %)	10 (5.1 %)	4 (0.6 %)	2.33 (0.48–11.28) 0.29
MCI	158 (17.5 %)	26 (13.3 %)	132 (18.6 %)	0.64 (0.35–1.17) 0.15
aMCIs	37 (4.1 %)	7 (3.6 %)	30 (4.2 %)	0.98 (0.32–3.07) 0.98
aMCIm	25 (2.8 %)	7 (3.6 %)	18 (2.5 %)	1.51 (0.43–5.34) 0.53
naMCIs	83 (9.2 %)	10 (5.1 %)	73 (10.3 %)	0.41 (0.17–0.99) 0.05
naMCIm	13 (1.4 %)	2 (1.0%)	11 (1.6 %)	0.34 (0.05–2.43) 0.28

Binary logistic regression models were used to calculate OR for dementia and MCI
A multinomial logistic model was used to calculate OR for the MCI subtypes
All calculations were adjusted for the following covariates: age, sex, level of education, hypertension, diabetes, and smoking habits
Abbreviations: eGFR estimated glomerular filtration rate, CI confidence interval, OR odds ratio
^aReference level for OR = Participants with eGFR ≥ 60 mL/min/1,73 m2 from baseline to follow up

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