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Table 3 Hazard Ratios for incident CKD in relation to anthropometric measures in women

From: The risk of chronic kidney disease in relation to anthropometric measures of obesity: A Swedish cohort study

Quartiles*

Q1

Q2

Q3

Q4

Q4 vs. Q1

p-value**

BMI (range, kg/m^2)

< 22.5

22.5-24.7

24.7-27.6

> 27.6

 

CKD1

0.8

1.0

1.3

2.6

 

HR-12

1

1.04 (0.74-1.45)

1.23 (0.89-1.69)

2.45(1.83-3.26)

<0.001

HR-23

1

0.99 (0.71-1.39)

1.05 (0.76-1.45)

1.65 (1.23-2.22)

<0.001

HR-34

1

0.99 (0.71-1.39)

1.05 (0.76-1.45)

1.63 (1.21-2.20)

0.001

WC (range, cm)

< 70

70-76

76-83

> 83

 

CKD1

0.8

0.8

1.2

2.9

 

HR-12

1

0.87 (0.61-1.25)

1.21 (0.89-1.66)

2.68 (2.03-3.55)

<0.001

HR-23

1

0.79 (0.55-1.14)

1.06 (0.77-1.45)

1.72 (1.29-2.30)

<0.001

HR-34

1

0.79 (0.55-1.13)

1.06 (0.77-1.45)

1.70 (1.27-2.27)

0.001

WHR (range)

< 0.76

0.76-0.79

0.79-0.82

> 0.82

 

CKD1

1.0

1.0

1.5

2.2

 

HR-12

1

1.00 (0.73-1.37)

1.43 (1.07-1.92)

2.13 (1.63-2.79)

<0.001

HR-23

1

0.93 (0.67-1.27)

1.22 (0.91-1.64)

1.42 (1.08-1.88)

0.013

HR-34

1

0.92 (0.67-1.27)

1.21 (0.90-1.61)

1.40 (1.06-1.85)

0.018

WHtR (range)

< 0.43

0.43-0.46

0.46-0.51

> 0.51

 

CKD1

0.7

0.9

1.4

2.8

 

HR-12

1

1.09 (0.75-1.56)

1.57 (1.12-2.20)

2.97 (2.18-4.05)

<0.001

HR-23

1

0.98 (0.68-1.42)

1.31 (0.93-1.84)

1.85 (1.34-2.56)

<0.001

HR-34

1

0.98 (0.68-1.41)

1.30 (0.92-1.82)

1.82 (1.32-2.52)

<0.001

BF% (range)

< 27.0

27.0-31.0

31.0-34.0

> 34

 

CKD1

0.7

0.9

1.3

2.8

 

HR-12

1

1.21 (0.84-1.75)

1.47 (1.06-2.04)

2.98 (2.18-4.07)

<0.001

HR-23

1

1.18 (0.81-1.70)

1.25 (0.90-1.74)

2.03 (1.48-2.81)

<0.001

HR-34

1

1.18 (0.81-1.70)

1.24 (0.89-1.73)

2.01 (1.45-2.78)

<0.001

Weight (range, kg)

< 60.0

60.0-66.0

66.0-74.0

> 74.0

 

CKD1

1.0

0.9

1.4

2.4

 

HR-12

1

0.89 (0.64-1.24)

1.32 (0.98-1.76)

2.31 (1.77-3.01)

<0.001

HR-23

1

0.84 (0.61-1.17)

1.17 (0.87-1.57)

1.65 (1.25-2.16)

<0.001

HR-34

1

0.84 (0.61-1.17)

1.18 (0.88-1.58)

1.64 (1.25-2.15)

<0.001

Height (range, cm)

< 160.0

160-164.0

164.0-168.0

> 168.0

 

CKD1

1.9

1.4

1.4

1.1

 

HR-12

1

0.80 (0.62-1.04)

0.90 (0.69-1.16)

0.85 (0.65-1.12)

0.252

HR-23

1

0.84(0.65-1.09)

0.94 (0.72-1.22)

0.94(0.71-1.23)

0.634

HR-34

1

0.85 (0.66-1.11)

0.96 (0.74-1.25)

0.97 (0.73-1.28)

0.807

  1. *Each quartile includes approximately 4110 individuals. **p-value <0.05 is considered significant
  2. 1CKD per 1000-person years; 2Cox-regression Hazard Ratio (HR) adjusted for age (95 % CI); 3HR-2 adjusted for age, use of antihypertensive medication, lipid-lowering medication, systolic blood pressure, smoking, alcohol consumption, low physical activity and diabetes (95 % CI); 4HR-3 adjusted for HR-2 plus low education, marital status and immigrant status (95 % CI)
  3. CKD Chronic kidney disease, BMI body mass index, WC waist circumference, WHR waist-hip ratio, WHtR waist-height ratio, BF % body-fat percentage, CI confidence interval
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BMC Nephrology

ISSN: 1471-2369

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