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Table 3 Cox regression analysis for the associations of various parameters and CVD mortality

From: Higher one-year achievement rate of serum phosphate associated with lower cardiovascular mortality in hemodialysis patients

Characteristics

Univariable

Multivariable

HR

P

HR

P

95%CI

Age

1.076

< 0.001

1.049

0.005

1.015–1.084

Male

2.053

0.026

   

Dialysis age (month)

0.999

0.868

   

Diabetes mellitus

2.773

0.001

1.979

0.039

1.036–3.778

Cardiovascular disease

3.463

< 0.001

2.79

0.002

1.468–5.303

History of malignant tumor

1.711

0.193

   

History of kidney transplantation

0.258

0.045

   

One-year achievement rate of serum phosphate

–

0.027

–

0.041

–

 Proportion = 0%

4.381

0.012

4.117

0.016

1.305–12.986

 Proportion = 25%

3.244

0.025

3.343

0.023

1.177–9.494

 Proportion = 50%

1.786

0.282

2.129

0.162

0.738–6.144

 Proportion = 75%

1.494

0.493

1.080

0.902

0.318–3.665

 Proportion = 100%

–

Ref

–

Ref

–

One-year mean of Hb(g/L)

0.988

0.366

   

One-year mean of Alb(g/L)

0.823

< 0.001

0.848

0.002

0.762–0.943

One-year mean of PAB(mg/L)

0.990

< 0.001

   

One-year mean of hs-CRP(mg/L)

1.025

0.009

   

One-year mean of NT-proBNP(pg/ml)

1.001

0.001

   

One-year mean of nPCR

0.184

0.044

   

One-year mean of spKt/V

0.113

0.009

   

One-year mean of URR

0.001

0.003

   
  1. Parameters including one-year mean of ALP, Hb, Alb, PAB, hs-CRP, NT-proBNP, nPCR, spKt/V and URR were enrolled using the mean value of four examinations in a year. The calculation of one-year achievement rate of serum phosphate was the target-achieving times divided by the total four times in 1 year
  2. Abbreviations: iPTH Intact parathyroid hormone, ALP Alkaline phosphatase, Alb Albumin, Hb Hemoglobin, PAB Prealbumin, hs-CRP High-sensitive C-reactive protein, nPCR Normalized protein catabolic rate, URR Urea reduction ratio