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Table 3 Nutritional outcomes in participants who completed the study

From: Oral sodium bicarbonate in people on haemodialysis: a randomised controlled trial

  

Baseline

Study end

 

Change during study

  

Mean

SD

Mean

SD

p valuea

Mean

SD

p valueb

Intervention (N = 15)

Body composition

 Dry weight (kg)

84.8

18.7

85.6

18.6

0.05

+ 0.9

1.6

0.08

 Lean tissue mass (%)

45.0

12.2

45.5

12.5

0.58

+ 0.5

3.3

0.07

 Fat mass (%)

38.8

9.4

38.3

9.8

0.40

−0.5

2.2

0.29

 Over-hydration (L)

1.2

2.4

1.4

2.0

0.60

+ 0.2

1.4

0.20

Muscle strength

 Handgrip (kg)

26.6

13.1

26.2

13.4

0.64

−0.4

3.4

0.32

Nutritional intake

 Energy (kcal/kg/d)

21.5

6.8

22.6

7.8

0.36

+ 1.1

4.4

0.79

 Protein (g/kg/d)

0.94

0.39

0.96

0.37

0.58

+ 0.02

0.14

0.76

 nPCR (g/kg/d)

1.12

0.32

1.14

0.23

0.72

+ 0.02

0.21

0.65

 Potassium (mg/kg/d)

27.6

9.8

29.2

10.9

0.34

+ 1.7

4.5

0.06

Control (N = 18)

Body composition

 Dry weight (kg)

77.9

15.6

77.7

15.9

0.64

−0.2

1.7

 

 Lean tissue mass (%)

51.8

13.7

50.2

12.1

0.041*

−1.6

2.9

 

 Fat mass (%)

33.4

9.9

33.8

9.3

0.52

+ 0.4

2.5

 

 Over-hydration (L)

1.7

1.7

2.4

2.0

0.001*

+ 0.7

0.8

 

Muscle strength

 Handgrip (kg)

31.2

10.9

29.7

10.1

0.034*

−1.5

3.0

 

Nutritional intake

 Energy (kcal/kg/d)

22.7

9.4

24.3

9.3

0.35

+ 1.6

6.0

 

 Protein (g/kg/d)

0.92

0.35

0.91

0.32

0.95

−0.01

0.28

 

 nPCR (g/kg/d)

1.06

0.20

1.12

0.23

0.36

+ 0.06

0.21

 

 Potassium (mg/kg/d)

30.3

11.9

28.2

10.6

0.23

−2.1

6.7

 
  1. aWithin groups (study end vs baseline)
  2. bBetween groups (change during study in intervention vs control group)
  3. nPCR: normalised protein catabolic rate.
  4. *Significant at p < 0.05