From: Oral sodium bicarbonate in people on haemodialysis: a randomised controlled trial
Baseline | Study end | Change during study | |||||||
---|---|---|---|---|---|---|---|---|---|
Mean | SD | Mean | SD | p valuea | Mean | SD | p valueb | ||
Intervention (N = 15) | |||||||||
Body composition | |||||||||
Dry weight (kg) | 84.8 | 18.7 | 85.6 | 18.6 | 0.05 | + 0.9 | 1.6 | 0.08 | |
Lean tissue mass (%) | 45.0 | 12.2 | 45.5 | 12.5 | 0.58 | + 0.5 | 3.3 | 0.07 | |
Fat mass (%) | 38.8 | 9.4 | 38.3 | 9.8 | 0.40 | −0.5 | 2.2 | 0.29 | |
Over-hydration (L) | 1.2 | 2.4 | 1.4 | 2.0 | 0.60 | + 0.2 | 1.4 | 0.20 | |
Muscle strength | |||||||||
Handgrip (kg) | 26.6 | 13.1 | 26.2 | 13.4 | 0.64 | −0.4 | 3.4 | 0.32 | |
Nutritional intake | |||||||||
Energy (kcal/kg/d) | 21.5 | 6.8 | 22.6 | 7.8 | 0.36 | + 1.1 | 4.4 | 0.79 | |
Protein (g/kg/d) | 0.94 | 0.39 | 0.96 | 0.37 | 0.58 | + 0.02 | 0.14 | 0.76 | |
nPCR (g/kg/d) | 1.12 | 0.32 | 1.14 | 0.23 | 0.72 | + 0.02 | 0.21 | 0.65 | |
Potassium (mg/kg/d) | 27.6 | 9.8 | 29.2 | 10.9 | 0.34 | + 1.7 | 4.5 | 0.06 | |
Control (N = 18) | |||||||||
Body composition | |||||||||
Dry weight (kg) | 77.9 | 15.6 | 77.7 | 15.9 | 0.64 | −0.2 | 1.7 | ||
Lean tissue mass (%) | 51.8 | 13.7 | 50.2 | 12.1 | 0.041* | −1.6 | 2.9 | ||
Fat mass (%) | 33.4 | 9.9 | 33.8 | 9.3 | 0.52 | + 0.4 | 2.5 | ||
Over-hydration (L) | 1.7 | 1.7 | 2.4 | 2.0 | 0.001* | + 0.7 | 0.8 | ||
Muscle strength | |||||||||
Handgrip (kg) | 31.2 | 10.9 | 29.7 | 10.1 | 0.034* | −1.5 | 3.0 | ||
Nutritional intake | |||||||||
Energy (kcal/kg/d) | 22.7 | 9.4 | 24.3 | 9.3 | 0.35 | + 1.6 | 6.0 | ||
Protein (g/kg/d) | 0.92 | 0.35 | 0.91 | 0.32 | 0.95 | −0.01 | 0.28 | ||
nPCR (g/kg/d) | 1.06 | 0.20 | 1.12 | 0.23 | 0.36 | + 0.06 | 0.21 | ||
Potassium (mg/kg/d) | 30.3 | 11.9 | 28.2 | 10.6 | 0.23 | −2.1 | 6.7 |