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Table 2 Estimated glomerular filtration rate by HIV and antiretroviral therapy (ART) status

From: Risk factors for impaired renal function in HIV-infected and HIV-uninfected adults: cross-sectional study in North-Western Tanzania

 

HIV-uninfected

(n = 654)1

HIV-infected ART naive

(n = 955)1

p* value2

HIV-infected on ART

(n = 333)1

p* value3

p* value4

eGFR (ml/min/1.73m2), mean (SD)5

111.2 (37.6)

109.7 (35.3)

0.06

129.5 (59.6)

< 0.001

< 0.001

Impaired renal function (eGFR< 60 mL/min/1.73m2), n (%)

37 (5.7)

77 (8.1)

0.045

21 (6.3)

0.20

0.76

eGFR categories (in eGFR > 135 mL/min/1.73m2)

 High normal (> 135)6

173 (26.5)

257 (26.9)

0.73

141 (42.3)

< 0.001

< 0.001

  Normal (90–135)

300 (45.9)

417 (43.7)

 

127 (38.1)

  

  Mildly decreased (60–89)

144 (22.0)

204 (21.4)

 

44 (13.2)

  

  Mildly to moderately decreased (45–59)

26 (4.0)

50 (5.2)

 

5 (1.5)

  

  Moderately to severely decreased (30–44)

8 (1.2)

17 (1.8)

 

10 (3.0)

  

  Severely decreased (15–29)

3 (0.5)

7 (0.7)

 

3 (0.9)

  

  Kidney failure (< 15)

0 (0.0)

3 (0.3)

 

3 (0.9)

  
  1. 1Missing eGFR results: One in HIV-uninfected, one in ART-naive HIV-infected and three in HIV-infected on ART; 2Comparing ART-naive HIV-infected with HIV-uninfected group; 3Comparing HIV-infected on ART with ART-naive HIV-infected group; 4Comparing HIV-infected on ART with HIV-uninfected group; 5Standard deviation; 6Renal hyper filtration
  2. *Adjusted for age, sex and fat-free mass