Skip to main content

Table 1 Sensitivity and specificity data obtained from the systematic review

From: Cost-effectiveness and value of information analysis of NephroCheck and NGAL tests compared to standard care for the diagnosis of acute kidney injury

TestA Parameter Mean value
(95% CI)
Mean (logit scale) Standard error (logit scale) Correlation for MVN distribution (logit scale)
NephroCheck
(N = 7 studies)
Sensitivity 0.75
(0.58 to 0.87)
1.1178 0.3967 −0.824
Specificity 0.61
(0.49 to 0.72)
0.4573 0.2567
NGAL plasma (BioPorto)
(N = 4 studies)
Sensitivity 0.76
(0.56 to 0.89)
1.1563 0.4615 −1.000
Specificity 0.67
(0.40 to 0.86)
0.6863 0.5659
NGAL urine Abbot ARCHITECT
(N = 6 studies)
Sensitivity 0.67
(0.58 to 0.76)
0.7273 0.2047 −0.5168
Specificity 0.72
(0.64 to 0.79)
0.9553 0.1909
NGAL urine BioPorto
(N = 8 studies)
Sensitivity 0.73
(0.65 to 0.80)
1.017 0.195 + 0.526
Specificity 0.83
(0.64 to 0.93)
1.562 0.511
  1. MVN Multi-Variable Normal
  2. ANote that some studies evaluated more than one of the candidate tests