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Table 1 Sensitivity and specificity data obtained from the systematic review

From: Cost-effectiveness and value of information analysis of NephroCheck and NGAL tests compared to standard care for the diagnosis of acute kidney injury

TestA

Parameter

Mean value

(95% CI)

Mean (logit scale)

Standard error (logit scale)

Correlation for MVN distribution (logit scale)

NephroCheck

(N = 7 studies)

Sensitivity

0.75

(0.58 to 0.87)

1.1178

0.3967

−0.824

Specificity

0.61

(0.49 to 0.72)

0.4573

0.2567

NGAL plasma (BioPorto)

(N = 4 studies)

Sensitivity

0.76

(0.56 to 0.89)

1.1563

0.4615

−1.000

Specificity

0.67

(0.40 to 0.86)

0.6863

0.5659

NGAL urine Abbot ARCHITECT

(N = 6 studies)

Sensitivity

0.67

(0.58 to 0.76)

0.7273

0.2047

−0.5168

Specificity

0.72

(0.64 to 0.79)

0.9553

0.1909

NGAL urine BioPorto

(N = 8 studies)

Sensitivity

0.73

(0.65 to 0.80)

1.017

0.195

+ 0.526

Specificity

0.83

(0.64 to 0.93)

1.562

0.511

  1. MVN Multi-Variable Normal
  2. ANote that some studies evaluated more than one of the candidate tests