Table 2 Characteristics at time of AKI diagnosis in septic patients with and without AKI progression

 SCr at AKI diagnosis, mg/dL

1.6 ± 0.5

1.7 ± 0.5

1.5 ± 0.5

0.022

 Peak SCr, mg/dL

1.8 ± 0.8

2.2 ± 0.9

1.6 ± 0.5

< 0.001

 Change in SCr ^a, mg/dL

1.0 ± 0.6

1.3 ± 0.7

0.7 ± 0.4

< 0.001

 SCys-C at AKI diagnosis, mg/L

1.5 ± 0.7

1.7 ± 0.7

1.3 ± 0.7

0.004

 AKI stage 1, n (%)

123 (82.6)

53 (84.1)

70 (81.4)

0.664

 AKI stage 2, n (%)

26 (17.4)

10 (15.9)

16 (18.6)

0.664

 AKI duration, d

2.0 (1.0-4.0)

3.5 (2.0-5.0)

1.0 (1.0-3.0)

< 0.001

 u[TIMP-2]*[IGFBP7], (μg/g Cr)²

1169.7 (426.6-3079.8)

2168.5 (1068.8-5274.9)

583.2 (293.6-1666.4)

< 0.001

 uKIM-1, μg/g Cr

3.1 (1.5-6.0)

5.0 (2.7-7.3)

2.1 (0.8-4.8)

< 0.001

 uIL-18, ng/g Cr

196.5 (79.5-664.5)

384.4 (89.4-1228.4)

131.5 (70.9-433.7)

0.017

 uACR, mg/g Cr

138.3 (47.8-476.5)

221.5 (76.6-546.2)

108.8 (33.9-302.3)

0.006

 ICU stay, d

7.0 (4.0-12.0)

7.0 (4.5-12.0)

6.0 (3.0-12.0)

0.296

 Acute dialysis, n (%)

23 (15.4)

23 (36.5)

0 (0.0)

< 0.001

 In-hospital death, n (%)

45 (30.2)

45 (71.4)

0 (0.0)

< 0.001