Fig. 2

Projected sample size calculation using a generalized estimating equation approach with at least four repeated measures of the primary outcome, according to varying base correlation of 0.2 to 0.7 (between repeated measures) and degree of missingness of 0.0 to 0.15. A sample size of 479 donor/recipient pairs (1:1 allocation to maternal and paternal door kidneys, represented by discontinuous blue line) will be required to achieve a power of 80% with a two-sided significance of 5% for detecting a difference of 0.10 between marginal proportions after applying continuity correction (and correlations score of 0.5 of at least 4 observations [for the composite outcome measures], and accounting for potential missingness of data of up to 10%)