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Table 3 Urinary pro-inflammatory and anti-inflammatory cytokines

From: Blood and urinary cytokine balance and renal outcomes at cardiac surgery

Urinary cytokines

Pre-op or post-op

Any day

non-CS-AKI

CS-AKI

P value

n

median

IQR

n

median

IQR

Pro-inflammatory cytokines

uIP-10

post-op

256

12.68

(6.31–25.29)

65

22.97

(9.71–61.26)

< 0.001

uIL-12p40

pre-op

258

0.94

(0–3.34)

65

2.53

(0–4.29)

0.035

uIL-12p40

post-op

256

2.87

(0–4.31)

65

4.47

(2.95–7.23)

< 0.001

uNGAL

post-op

247

135.09

(68.7–306.8)

64

234.44

(136.94–429.46)

< 0.001

Anti-inflammatory cytokines

uTNFsr1

pre-op

257

0.53

(0.3–0.87)

65

0.70

(0.42–1.07)

0.044

uTNFsr1

post-op

254

6.66

(4.4–8.71)

65

7.70

(5.31–10.28)

0.020

uTNFsr2

pre-op

257

0.83

(0.34–1.52)

65

1.26

(0.48–2.06)

0.020

uTNFsr2

post-op

255

8.08

(5.9–10.08)

65

9.56

(6.41–12.3)

0.018

uIL-1RA

post-op

247

8616.30

(3828.3–18,027.3)

64

13,274.55

(5696.63–31,703.93)

0.024

  1. pre-op Preoperative, post-op Postoperative, CS-AKI Cardiac surgery acute kidney injury, n Number of patients, uIP-10 Urinary interferon gamma - induced protein-10, uIL-12p40 Urinary interleukin-12 subunit p40, uNGAL Urinary neutrophil gelatinase-associated lipocalin, uTNFsr1 Urinary tumor necrosis factor soluble receptor 1, uTNFsr2 Urinary tumor necrosis factor soluble receptor 2, uIL-1RA Urinary interleukin-1 receptor antagonist