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Table 2 Comparison between patients with and without anaemia

From: Evaluation of recombinant human erythropoietin responsiveness by measuring erythrocyte creatine content in haemodialysis patients

 

Haemoglobin

P Value

<10 g/dL

(n = 27)

≥10 g/dL

(n = 56)

Age (years)

71.4 ± 13.5

71.9 ± 15.1

0.87

Gender (male/female)

14/13

42/14

0.05

Haemodialysis time (hours/week)

16.4 ± 4.1

15.7 ± 4.2

0.45

Intradialytic ultrafiltration rate (ml/hour/kg)

9.3 ± 3.1

8.6 ± 2.9

0.35

Kt/v

1.8 ± 0.5

1.7 ± 0.5

0.5

Erythrocyte creatine (μmol/gHb)

2.07 ± 0.73

1.60 ± 0.41

0.0003

ESA dose (units/kg/week)

152.4 ± 62.9

82.2 ± 45.5

0.0001

Erythropoietin resistance index (units/kg/week/g/dL)

17.6 ± 7.9

7.6 ± 4.4

0.0001

Red blood cell (x 104μL)

288.0 ± 35.4

358.8 ± 33.1

0.0001

Haematocrit (%)

27.2 ± 4.4

34.5 ± 2.4

0.0001

Haemoglobin (g/dL)

8.9 ± 0.9

11.0 ± 0.7

0.0001

MCV

98.6 ± 6.7

97.2 ± 5.6

0.32

MCH

31.2 ± 2.4

30.9 ± 2.0

0.54

MCHC

31.6 ± 0.9

31.8 ± 0.7

0.42

Reticulocyte (%)

16.2 ± 5.1

15.1 ± 4.8

0.31

Haptoglobin (g/dL)

88.5 ± 51.1

97.3 ± 50.4

0.46

Transferrin saturation (%)

24.4 ± 12.9

29.5 ± 17.5

0.19

Ferritin (ng/mL)

110.4 ± 88.0

126.6 ± 114.8

0.52

Iron deficiency (present/ absent)

18/9 (67%)

29/27 (52%)

0.2

Iron supplement (present/ absent)

9/18 (33%)

13/43 (23%)

0.43

Intact parathyroid hormone (pg/mL)

146.7 ± 99.0

155.1 ± 104.2

0.73

Serum calcium (mg/dL)

9.5 ± 0.5

9.5 ± 0.5

0.98

Serum phosphorus (mg/dL)

4.5 ± 1.2

5.1 ± 1.4

0.085

Albumin (g/dL)

3.6 ± 0.4

3.6 ± 0.3

0.39

C-reactive protein (mg/dL)

0.35 ± 0.29

0.31 ± 0.37

0.61

  1. Data are represented as mean ± SD. ESA Eythropoiesis stimulating agent, Kt/v Urea clearance, MCH Mean cell haemoglobin, MCHC Mean cell haemoglobin concentration, MCV Mean cell volume