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Table 3 Correlation between renal parameters and iron status parameters in patients with β-Thalassemia Major and their subgroups according to the chelation treatment, in the current study

From: Renal function in β-thalassemia major patients treated with two different iron-chelation regimes

Parameters Correlated

Study subgroups (chelation treatment)

Chelator

DFX

n = 26

DFO +/−DFP

n = 10

Total

n = 36

uNAG vs. Total amount of total iron transfused for prior 10 years

r = 0.02, p = 0.89

r = 0.7, p = 0.02

r = 0.08, p = 0.6

uNAG vs. Mean serum ferritin for the prior 10 years

r = − 0.028, p = 0.88

r = 0.62, p = 0.07

r = − 0.35, p = 0.03

uNAG vs. Heart T2* MRI ms.

r = 0.54, p = 0.01

r = 0.2517, p = 0.4

r = 0.47, p < 0.01

Urinary Ca/Cr ratio vs Hb levels

r = 0.32, p = 0.1

r = 0.7, p = 0.018

r = 0.41, p = 0.001

Urinary Ca/Cr ratio vs. Mean serum ferritin for the prior 10 year

r = − 0.35, p = 0.03

r = − 0.68, p = 0.03

r = − 0.35, p = 0.03

Urinary Ca/Cr ratio vs. Amount of iron transfused over the prior10 years

r = −0.12, p = 0.5

r = − 0.55, p = − 0.09

r = − 0.4, p = − 0.014