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Table 3 Correlation between renal parameters and iron status parameters in patients with β-Thalassemia Major and their subgroups according to the chelation treatment, in the current study

From: Renal function in β-thalassemia major patients treated with two different iron-chelation regimes

Parameters Correlated Study subgroups (chelation treatment)
Chelator DFX
n = 26
DFO +/−DFP
n = 10
Total
n = 36
uNAG vs. Total amount of total iron transfused for prior 10 years r = 0.02, p = 0.89 r = 0.7, p = 0.02 r = 0.08, p = 0.6
uNAG vs. Mean serum ferritin for the prior 10 years r = − 0.028, p = 0.88 r = 0.62, p = 0.07 r = − 0.35, p = 0.03
uNAG vs. Heart T2* MRI ms. r = 0.54, p = 0.01 r = 0.2517, p = 0.4 r = 0.47, p < 0.01
Urinary Ca/Cr ratio vs Hb levels r = 0.32, p = 0.1 r = 0.7, p = 0.018 r = 0.41, p = 0.001
Urinary Ca/Cr ratio vs. Mean serum ferritin for the prior 10 year r = − 0.35, p = 0.03 r = − 0.68, p = 0.03 r = − 0.35, p = 0.03
Urinary Ca/Cr ratio vs. Amount of iron transfused over the prior10 years r = −0.12, p = 0.5 r = − 0.55, p = − 0.09 r = − 0.4, p = − 0.014