Table 1 Baseline characteristics of the study patients according to the optimal cutoff point of galectin–3
Characteristic | Study population (n = 506) | Galectin–3 (ng/ml) | ||
|---|---|---|---|---|
≤ 8.65 (n = 79) | > 8.65 (n = 427) | P | ||
Age, years | 58 (47–66) | 56 (43–63) | 58 (48–66) | 0.07 |
Male, n (%) | 270 (53.4) | 43 (54.4) | 227 (53.2) | 0.84 |
Time on dialysis, months | 51 (25–77) | 54 (31–71) | 48 (24–79) | 0.44 |
Cause of end–stage renal disease, n (%) | 0.16 | |||
Diabetes | 133 (26.3) | 22 (27.8) | 111 (26.0) | |
Glomerulonephritis | 205 (40.5) | 28 (35.4) | 177 (41.5) | |
Hypertension | 94 (18. 6) | 21 (26.6) | 73 (17.1) | |
Other | 74 (14.6) | 8 (10.1) | 66 (15.5) | |
Systolic blood pressure, mmHg | 150 (135–160) | 140 (125–155) | 150 (140–160) | < 0.05 |
Diastolic blood pressure, mmHg | 80 (80–90) | 80 (80–90) | 80 (80–90) | 0.07 |
Hemoglobin, g/l | 110 (101–118) | 111 (100–118) | 110 (101–118) | 0.49 |
Albumin, g/l | 40.7 (39.0–42.4) | 40.7 (38.9–41.9) | 40.7 (39.0–42.5) | 0.66 |
Single–pool Kt/V | 1.37 (1.22–1.53) | 1.38 (1.22–1.55) | 1.37 (1.22–1.53) | 0.92 |
Alkaline phosphatase, u/l | 85 (69–117) | 86 (72–118) | 85 (69–117) | 0.78 |
Potassium, mmol/l | 4.96 (4.42–5.56) | 5.01 (4.51–5.40) | 4.96 (4.41–5.58) | 0.85 |
Sodium, mmol/l | 134.0 (131.8–136.3) | 134.5 (131.9–135.8) | 133.9 (131.8–136.4) | 0.88 |
Calcium, mmol/l | 2.36 ± 0.17 | 2.38 ± 0.17 | 2.36 ± 0.17 | 0.34 |
Phosphorus, mmol/l | 1.99 (1.58–2.39) | 1.94 (1.55–2.36) | 1.99 (1.61–2.40) | 0.28 |