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Table 2 The differences of clinical characteristics in the subgroup divided by the quartile range of g-Streptococcus

From: Intestinal dysbiosis featuring abundance of Streptococcus associates with Henoch-Schönlein purpura nephritis (IgA vasculitis with nephritis) in adult

Parameter

g-Streptococcus

Low level group (L)

moderate level group (M)

high level group (H)

P

≤0.12%

> 0.12%, but ≤ 4.78%

> 4.78%

L vs. M

L vs. H

M vs. H

Numbers (%)

7 (26.9)

13 (50)

6 (23.1)

   

Male (%)

4 (57.1)

5 (38.5)

4 (66.7)

0.642

1.000

0.350

M1 (%)

7 (100)

11 (84.6)

5 (83.3)

0.521

0.462

1.000

E1 (%)

2 (28.5)

2 (15.4)

2 (33.3)

0.587

1.000

0.557

S1 (%)

1 (14.3)

7 (53.8)

4 (66.7)

0.158

0.103

1.000

T1–2 (%)

0 (0)

1 (7.6)

0 (0)

1.000

1.000

C1–2 (%)

1 (14.3)

4 (30.7)

4 (66.7)

0.613

0.103

0.319

Age (years)

33.0 ± 11.8

30.6 ± 10.6

24.0 ± 15.0

0.675

0.190

0.274

SBP (mmHg)

133.2 ± 23.2

115.2 ± 14.3

122.3 ± 24.4

0.407

0.975

0.466

DBP (mmHg)

84.4 ± 15.5

78.2 ± 10.5

68.5 ± 11.8

0.576

0.663

0.986

u-Pro (g/24 h)

0.66 ± 0.55

1.04 ± 1.17

2.30 ± 2.43

0.577

0.050

0.092

u-RBCs (/Hp)

58.6 ± 128.4

84.9 ± 120.4

402.3 ± 508.5

0.832

0.027

0.022

HGB (g/L)

131.3 ± 17.7

129.9 ± 12.4

120.6 ± 27.8

0.866

0.326

0.330

Alb (g/L)

45.1 ± 6.6

39.5 ± 5.8

34.2 ± 13.4

0.165

0.027

0.206

sCr (μmol/L)

133.4 ± 122.0

72.2 ± 34.0

102.3 ± 60.4

0.220

0.608

0.666

eGFR (mL/min/1.73m2)

78.6 ± 33.2

109.7 ± 30.4

100.5 ± 45.7

0.092

0.506

0.455

IgA (μg/mL)

899.8 ± 609.9

987.3 ± 860.9

379.26 ± 134.3

0.846

0.377

0.237

Gd-IgA1 (ng/mL)

767.4 ± 264.3

887.5 ± 389.9

913.3 ± 239.7

0.577

0.643

0.927

Gd-IgA1/IgA (‰)

1.1 ± 0.6

1.7 ± 1.6

4.8 ± 3.2

0.573

0.015

0.018

  1. Abbreviation: M mesangial proliferation, E endocapillary proliferation, S segmental glomerulosclerosis, T tubular atrophy or interstitial fibrosis, C crescents, SBP systolic blood pressure, DBP diastolic blood pressure, u-Pro urine protein, u-RBCs urinary red blood cells, HGB hemoglobin, Alb serum albumin, sCr serum creatinine, eGFR estimate glomerular filtration rate, Gd-IgA1 galactose-deficient IgA