From: SARS-CoV-2 infection increases risk of acute kidney injury in a bimodal age distribution
 | Total | No AKI | AKI |
---|---|---|---|
6874 | 4155 (60.5) | 2719 (39.6) | |
Age, years, median (IQR) | 60 (44–71) | 55 (39–68) | 65 (53–75) |
Age Categories | |||
  < 20 years | 621 (9) | 450 (11) | 171 (6) |
 20 to < 40 years | 772 (11) | 615 (15) | 157 (6) |
 40 to < 60 years | 2038 (30) | 1359 (33) | 679 (25) |
 60 to < 80 years | 2647 (39) | 1375 (33) | 1272 (47) |
  ≥ 80 years | 796 (12) | 356 (9) | 440 (16) |
BMI categorya | |||
 Underweight | 137 (2) | 78 (2) | 59 (2) |
 Normal | 1270 (19) | 832 (20) | 438 (16) |
 Overweight | 1620 (24) | 965 (23) | 655 (24) |
 Obesity | 1666 (24) | 921 (22) | 745 (27) |
 Severe Obesity | 552 (8) | 302 (7) | 250 (9) |
 Unknown | 1629 (24) | 1057 (25) | 572 (21) |
Sex (male)b | 3998 (58) | 2327 (56) | 1671 (62) |
Race/Ethnicityb | |||
 White, non-Hispanic | 2189 (32) | 1273 (31) | 916 (34) |
 White, Hispanic | 523 (8) | 335 (8) | 188 (7) |
 Black, non-Hispanic | 1353 (20) | 700 (17) | 653 (24) |
 Black, Hispanic | 50 (0.7) | 37 (0.9) | 13 (0.5) |
 Asian American | 95 (1) | 53 (1) | 42 (2) |
 South Asian | 1027 (15) | 842 (20) | 185 (7) |
 East Asian | 36 (0.5) | 20 (0.5) | 16 (0.6) |
 West Asian | 106 (2) | 61 (2) | 45 (2) |
 Other/mixed | 845 (12) | 511 (12) | 334 (12) |
 White, ethnicity not specified | 402 (6) | 184 (4) | 218 (8) |
 Black, ethnicity not specified | 76 (1) | 36 (0.9) | 40 (2) |
Location of Center | |||
 United States | 4984 (73) | 2872 (69) | 2112 (78) |
 Non-United States | 1890 (28) | 1283 (31) | 607 (22) |
Number of Comorbidities, median (IQR) | 2 (1, 4) | 2 (1, 4) | 3 (1, 5) |
Healthy (no comorbidities) | 1356 (20) | 1020 (25) | 336 (12) |
Comorbiditiesc | |||
 Hypertension | 3404 (50) | 1722 (41) | 1682 (62) |
 Diabetes | 2279 (33) | 1169 (28) | 1110 (41) |
 Heart Disease | 1577 (23) | 732 (18) | 845 (31) |
Chronic Kidney Disease | 754 (11) | 339 (8) | 415 (15) |
 Asthma | 757 (11) | 478 (12) | 279 (10) |
 Chronic lung disease, not asthma | 1395 (20) | 770 (19) | 625 (23) |
 Stroke/ Neurological disorder | 818 (12) | 447 (11) | 371 (14) |
 Cancer | 904 (13) | 497 (12) | 407 (15) |
Pre-Hospital Medications | |||
 ACE-I/ARBs | 1497 (22) | 756 (18) | 741 (27) |
 Diuretics | 179 (3) | 77 (2) | 102 (4) |
 NSAIDs | 610 (9) | 377 (9) | 233 (9) |
 Aspirin | 1127 (16) | 554 (13) | 573 (21) |
Severity of Diseased | |||
 Mild disease | 2710 (39) | 1950 (47) | 760 (28) |
 Moderate disease | 2064 (30) | 1389 (33) | 675 (25) |
 Severe disease | 2100 (31) | 816 (20) | 1284 (47) |
Ever admitted to ICU (yes) | 4075 (59) | 2149 (52) | 1926 (71) |
SARS-CoV2 Testing | |||
 PCR+ | 6409 (93) | 3858 (93) | 2551 (94) |
 Antibody+ | 98 (1) | 45 (1) | 53 (2) |
 PCR and antibody+ | 367 (5) | 252 (6) | 115 (4) |