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Table 5 90-days uni- and multivariable survival analysis

From: Acute kidney injury following major emergency abdominal surgery – a retrospective cohort study based on medical records data

 

Unadjusted HR

(95% CI)

P -value

Adjusted HR

(95% CI)

P -value

Acute Kidney Injury

5.19 (3.35–8.03)

 < 0.0001

4.45 (2.69–7.39)

 < 0.0001

Baseline s-creatinine, µmol l −1

2.77 (1.92- 3.98)

 < 0.0001

2.20 (1.35–3.59)

0.002

Age group

 

 < 0.0001

 

 < 0.0001

  < 60

1.00 (ref)

1.00 (ref)

  > 60–70

3.39 (1.32–8.74)

1.53 (0.52–4.49)

  > 70–80

8.55 (3.57–20.45)

6.23 (2.37–16.38)

  > 80

9.37 (3.88–22.63)

5.16 (1.92–13.89)

Female

1.30 (0.83–2.03)

0.25

1.18 (0.72–1.95)

0.43

Charlson Comorbidity Index

 

 < 0.0001

 

0.001

  0

1.00 (ref)

1.00 (ref)

  1–2

2.88 (1.60–5.17)

2.64 (1.37–5.07)

  > 2

5.58 (3.02–10.31)

4.37 (2.17–8.81)

Type of Surgery

 

0.06

 

0.10

  Upper gastrointestinal

1.00 (ref)

1.00 (ref)

  Small intestine with resection

0.52 (0.25–1.07)

0.60 (0.27–1.31)

  Colon with resection

0.57 (0.26–1.24)

0.91 (0.37–2.27)

  Laparotomy (no resection)

0.34 (0.17–0.68)

0.39 (0.18–0.88)

  Combined small intestine and colon

0.48 (0.18–1.30)

1.29 (0.45–3.67)

  Other

0.21 (0.026–1.59)

0.44 (0.06–3.53)

Peritoneal Contamination

 

0.002

 

0.35

  None

1.00 (ref)

1.00 (ref)

  Minimal

1.45 (0.77–2.72)

1.35 (0.69–2.65)

  Local pus/abscess

1.83 (0.88–3.79)

1.63 (0.73–3.63)

  Diffuse pus or faeces

2.83 (1.67–4.80)

1.26 (0.621–2.54)

qSOFA a

 

0.04

 

0.18

  0

1.00 (ref)

1.00 (ref)

  1

1.01 (0.60–1.70)

0.95 (0.56–1.62)

  ≥ 2

2.28 (1.15–4.50)

1.90 (0.92–3.93)

  1. 95% CI 95% confidence interval, HR Hazard ratio, ref reference level, aqSOFA, quick Sepsis Organ Failure Assessment. The multivariable survival analysis was adjusted for acute kidney injury, baseline s-creatinine, age, sex, Charlson Comorbidity Index, type of surgery, peritoneal contamination, and quick Sepsis Organ Failure Assessment score