Table 2 Clinical parameters before and after intervention (ITT set)
Parameters | Low-sodium+placebo (n = 28) | Medium-sodium+SPL (n = 28) | Low-sodium+SPL (n = 28) | P among groups | |
|---|---|---|---|---|---|
Primary endpoint 24-h urine protein (g/d) | Before intervention | 0.37 (0.23,0.70) | 0.44 (0.33,0.71) | 0.35 (0.26,0.73) | 0.365 |
At 12 weeks | 0.23 (0.16,0.51) | 0.29 (0.17,0.50) | 0.31 (0.22,0.60) | 0.791 | |
Change between pre- and post- intervention | −0.06 (− 0.24,0) | −0.17 (− 0.25,-0.01) | − 0.12 (− 0.27,0.05) | 0.760 | |
P within group | 0.004 | 0.020 | 0.013 | Â | |
24-h urine protein to creatinine ratio (g/mol) | Before intervention | 30.54 (18.83,77.38) | 54.00 (28.77, 81.30) | 33.12 (25.90, 58.68) | 0.248 |
|  | At 12 weeks | 25.40 (14.12,50.71) | 24.72 (18.49,44.10) | 29.20 (15.69,62.39) | 0.949 |
|  | Change between pre- and post- intervention | −3.72 (−16.42,1.04) | −15.85 (−41.40,-3.27) | −11.70 (−22.88,10.92) | 0.118 |
| Â | P within group | 0.012 | 0.011 | 0.026 | Â |