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Table 3 Multivariate Cox regression analysis of factors affecting death censored five-year graft survival

From: Post-transplant outcomes in recipients of living donor kidneys and intended recipients of living donor kidneys

 

Univariate

Multivariate

Parameter

P value

Hazard ratio (95% confidence interval)

Parameter estimate

Standard error

Chi-square

P value

Hazard ratio (95% confidence interval)

LD vs DD1

  LD

0.723

0.812 (0.257—2.566)

     

  Recipient age (per year)

0.594

1.011 (0.970—1.054)

     

  Donor age (per year)

0.464

1.014 (0.976—1.054)

     

  Acute rejection

0.322

1.830 (0.552—6.066)

     

  Delayed graft function

0.137

2.466 (0.749—8.116)

1.026

0.494

4.310

0.037

2.792

(1.059—7.362)

  Caucasian race

0.277

1.730 (0.644—4.651)

     

  Diabetic Nephropathy as cause for ESKD

0.595

0.692 (0.178—2.694)

     

LD vs DD0

  LD

0.029

0.408 (0.183 – 0.913)

-1.072

0.385

7.756

0.005

0.342 (0.161—0.728)

  Recipient age (per year)

0.140

1.022 (0.993 – 1.051)

     

  Donor age (per year)

0.822

0.998 (0.979 – 1.017)

     

  Acute rejection

0.002

2.855 (1.467 – 5.555)

0.967

0.332

8.458

0.003

2.632 (1.371—5.052)

  Delayed graft function

0.099

1.633 (0.910 – 2.930)

0.591

0.287

4.237

0.039

1.807 (1.029—3.173)

  Caucasian race

0.802

1.076 (0.607 – 1.907)

     

  Diabetic Nephropathy as cause for ESKD

0.102

1.631 (0.907 – 2.933)

0.579

0.277

4.359

0.036

1.785 (1.036—3.076)

LD vs DD1 + DD0

  LD

0.037

0.441 (0.204 – 0.955)

-0.905

0.376

5.795

0.016

0.404 (0.193—0.845)

  Recipient age (per year)

0.328

1.012 (0.988 – 1.038)

     

  Donor age (per year)

0.884

1.001 (0.983 – 1.020)

     

  Acute rejection

0.001

2.679 (1.482 – 4.844)

0.933

0.296

9.920

0.001

2.542 (1.423 -4.544)

  Delayed graft function

0.037

1.742 (1.034 – 2.935)

0.608

0.260

5.439

0.019

1.838 (1.102—3.064)

  Caucasian race

0.552

1.169 (0.699 – 1.955)

     

  Diabetic Nephropathy as cause for ESKD

0.090

1.621 (0.927 – 2.834)

0.548

0.259

4.483

0.034

1.731 (1.042- 2.878)

DD1 v DD0

  DD1

0.091

0.555 (0.281—1.097)

-0.698

0.359

3.776

0.052

0.498 (0.246—1.006)

  Recipient age (per year)

0.356

1.011 (0.988—1.034)

     

  Donor age (per year)

0.224

1.011 (0.993—1.029)

     

  Acute rejection

0.000

3.157 (1.728—5.767)

1.09

0.314

12.053

0.001

2.973 (1.607 –

5.500)

  Delayed graft function

0.006

2.049 (1.224—3.429)

0.65

0.274

5.645

0.018

1.916 (1.121—3.275)

  Caucasian race

0.870

1.045 (0.615—1.777)

     

  Diabetic Nephropathy as cause for ESKD

0.010

2.015 (1.185—3.425)

0.645

0.299

4.651

0.031

1.906 (1.061—3.426)

  1. ESKD End-stage kidney disease. For DD0, DD1, LD definitions see text
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