Variables | Total | High cortisol group (n=67) | Low cortisol group (n=66) | P value |
---|---|---|---|---|
Serum cortisol (μg/dL) | 10.2±3.6 | 12.9±2.5 | 7.4±1.9 | <0.001 |
ACTH (pg/mL) | 31.7 [19.8, 47.1] | 38.3 [23, 53.7] | 24.9 [17.5, 37.8] | 0.001 |
Age (yr) | 62.9±10.5 | 63.4±10.1 | 62.4±11.0 | 0.594 |
Male (%) | 65 (48.9) | 31 (46.3) | 34 (51.5) | 0.545 |
HD duration (yr) | 4.2 [1.8, 7.7] | 4.2 [2.2, 8.3] | 4.3 [1.3, 6.9] | 0.439 |
Diabetes mellitus (%) | 91 (68.4) | 49 (73.1) | 42 (63.6) | 0.239 |
Hypertension (%) | 127 (95.5) | 65 (97.0) | 62 (93.9) | 0.441 |
Cardiovascular disease (%) | 66 (49.6) | 40 (59.7) | 26 (39.4) | 0.019 |
Dose of erythropoietin (IU/week) | 8000 [4000, 12000] | 10000 [4000, 12000] | 4500 [3000, 9000] | 0.008 |
Body mass index (kg/m2) | 23.0±4.3 | 23.1±3.9 | 22.9±4.7 | 0.806 |
Interdialytic weight gain (kg) | 2.36±0.85 | 2.39±0.83 | 2.34±0.88 | 0.736 |
Kt/V | 1.68±0.3 | 1.62±0.28 | 1.68±0.35 | 0.348 |
Plasma hemoglobin (g/dL) | 10.5±1.0 | 10.6±1.1 | 10.4±0.8 | 0.287 |
Glucose (mg/dL) | 168.5±76.4 | 174.4±83.3 | 162.4±68.8 | 0.366 |
Serum albumin (g/dL) | 3.8±0.4 | 3.8±0.3 | 3.7±0.4 | 0.156 |
Sodium (mEq/L) | 138.3±3.8 | 137.5±3.9 | 139.0±3.6 | 0.024 |
Potassium (mEq/L) | 4.7±0.8 | 4.8±0.7 | 4.7±0.8 | 0.674 |
Serum calcium (mg/dL) | 8.9±0.8 | 9.0±0.7 | 8.7±0.9 | 0.134 |
Serum phosphorus (mg/dL) | 4.4±1.4 | 4.5±1.3 | 4.3±1.6 | 0.429 |
Intact PTH (pg/mL) | 279 [113.1, 484.3] | 290 [143, 433.3] | 257.7 [99.7, 526.7] | 0.568 |
Total cholesterol (mg/dL) | 133.7±35.4 | 135.1±39.6 | 132.4±30.8 | 0.664 |
LDL-cholesterol (mg/dL) | 72.3±23.7 | 72.4±26.4 | 72.1±20.8 | 0.943 |
C-reactive protein (mg/L) | 1.4 [0.7, 3.2] | 1.5 [1.0, 2.9] | 1.2 [0.6, 3.3] | 0.311 |
LVH (%) | 78 (77.2) | 40 (75.5) | 38 (79.2) | 0.658 |
LVSD (%) | 18 (13.5) | 14 (25.9) | 4 (8.0) | 0.016 |
LVDD (%) | 53 (39.8) | 26 (52.0) | 27 (55.1) | 0.757 |