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Table 5 Biochemical parameters of sepsis and renal injury among the patients

From: Expression and 7-day time course of circulating microRNAs in septic patients treated with nephrotoxic antibiotic agents

Parameter

Day

Vancomycin

IQR

Gentamicin

IQR

Other ATBs

IQR

P

NGAL (μg/L)

1

240

120–1150

290

136–937

468

210–775

0.558

NGAL (μg/L)

4

170

100–520

217

105–351

438

292–488

0.105

NGAL (μg/L)

7

130

75–430

157

125–476

358

200–583

0.172

Screa (μmol/L)

1

71

59–165

116

87–166

156

131–239

0.063

Screa (μmol/L)

4

59

45–139

85

68–98

129

75–226

0.064

Screa (μmol/L)

7

62

42–225

78

57–108

101

66–160

0.378

IL-6 (ng/L)

1

51

31–109

310

61–5500

176

73–1073

0.107

IL-6 (ng/L)

4

34

13–109

47

19–185

55

25–108

0.598

IL-6 (ng/L)

7

23

11–92

27

12–152

66

20–289

0.551

PCT (μg/L)

1

0.5

0.2–9.8

7.9

0.7–22.7

2.5

1.5–5.9

0.162

PCT (μg/L)

4

0.3

0.1–2.7

1.5

0.3–1.8

1.5

0.5–5.1

0.297

PCT (μg/L)

7

0.2

0.0–3.0

0.7

0.1–1.8

0.7

0.2–1.3

0.530

  1. Abbreviations: IL-6 interleukin 6, IQR interquartile range, NGAL neutrophil gelatinase–associated lipocalin, PCT procalcitonin, Screa serum creatinine. P values derived from the Kruskal–Wallis test. Data are presented as medians and interquartile ranges. IL-6 on day 7 in the gentamicin group is presented for 19 patients; day 7 data for IL-6, Screa, and PCT are presented for 18 patients in the ATB group